July 21 2004 Cosanti Foundation long time staff m

first_imgJuly 21, 2004Cosanti Foundation long time staff member Roger Tomalty is in Venice, Italy, to teach a Silt Cast Workshop at the IUAV School of Architecture. [Photo: Antonio Fragiacomo & text: Matteo Di Michele]Cosanti Foundation long time staff member Roger Tomalty is in Venice, Italy, to teach a Silt Cast Workshop at the IUAV School of Architecture. [Photo: Antonio Fragiacomo & text: Matteo Di Michele] [left photo] The IUAV School of Architecture in Venice is one of the most prestigious architecture schools in Italy. It has started an intensive summer program of innovative sessions with the intention of facilitating the expressive capacities of its students by putting a consistent amount of space and tools at their disposal. Important architects from all around the world were invited to participate. One of these courses, mandatory to graduate from the School, is about Paolo Soleri and Arcosanti. [right photo] Marco Felici introduces the students to Paolo Soleri’s LEAN ALTERNATIVE. [left photo: IUAV, right photo: Antonio Fragiacomo & text: Matteo Di Michele] The course has been organized and delivered by Architect Antonio Fragiacomo, Structural Engineer Marco Felici and Cosanti Research Associate Roger Tomalty, with the precious help of Daniela Bruni, Maurizio Ranzi (Roma Tre University), Sandra Suatoni (Istituto Italiano Per La Grafica), Lorenzo Alfieri, Robert Clyde and Arcosanti residents Mary Hoadley and Matteo Di Michele. [Photo: Antonio Fragiacomo & text: Matteo Di Michele]last_img read more

September 12 2006 New York Ground Zero Theologi

first_imgSeptember 12, 2006 New York Ground Zero Theological Terrorism An old, old story From vol. 7, pg. 112 of Storia D’Italia by Montanelli On the first crusade, year 1099 New York Ground Zero Theological Terrorism An old, old story From vol. 7, pg. 112 of Storia D’Italia by Montanelli On the first crusade, year 1099 There were no more than 12000 crusaders that, in July 1099, after a three-year campaign, got to camp under the walls of Jerusalem. Their emotion in sighting the sacred city changed into surprise when the presiding Muslim garrison declared to be ready for an armistice. That garrison wasn’t Turkish but Arab, because the previous year Jerusalem had been retaken from the Selgiuchi by the Fatimidi, who had never confronted the Franchi. But they didn’t accept the offer, perhaps because they thought a non-violent negotiation would have ruined their triumph. Therefore they demanded unconditional surrender. The defenders, about 1000 men, resisted for 40 days. Then they surrendered. “Then,” a witness present, Raimondo de Agiles, famous for his zeal and his piety said, “one saw marvelous (meravigliose) things. The Muslims were beheaded or killed by harrow or thrown from the towers. Others were tortured for days and days and then torched. The streets were strewn with heads, chopped hands and feet.” Those “marvelous” things lasted until the total consummation of the 70,000 citizens of Jerusalem, including the Jews. They were crowded and burned inside the synagogues. Then the crusaders gathered in the grotto of the Santa Sepolcro that had hosted the remains of Christ, who had come into the world to preach misericordia and there they cried joyfully, finally feeling worthy of him.[Image: Arcosanti Graphics & text: selected by Paolo Soleri] The Secular Cathedral A transnational structure aiming at a (distant) more equitable consumerism. A habitat for remembering, living, working, learning and divertimento. Part of the divertimento is the battery of slides evacuating the cathedral in 20 minutes or so (20,000 people?). The mantle generated by the 40 or so slides defines an umbrella-parasol of about 400 meters diameter covering a multi-story urban life that the citizens of New York would think about and the designer-builder would try to satisfy (the analogy with the Piero della Francesca generous mantle of mother sheltering the flock of her children). The circular pond is the speed breaker for the people evacuating the cathedral from most of its stories. The evacuation is pure gravity effect descent, with no mechanical equipment, no energy use, in fact no need of leg use. It is a very large combination of children’s playground and swimming pool slide, of roller coaster rides and of emergency slides in air passenger planes.[Image: Arcosanti Graphics & text: Paolo Soleri] Time: for instance from floor 30 one can reach a restaurant or a shop on Barclay St., West St., Liberty St., etc. in less than one minute. This is part of the appeal to visitors and employees offered by the multi-level grounds of the cathedral. Magnetic levitation propulsion is suggested for the power driven ascent conveyances. Besides escalators and elevators, gondolas could be propelled on wider slides Functions: the first 4-5 floors are of the “N.Y., N.Y.” format. The typical busybody going about of the Manhattan people. Those floors ring the area and also serve as entrance to the inner-urban celebratory spaces where business, cultural gatherings, concerts, theater let the visitors commingle, enjoy and learn. This is a multi-story inner space under the cover of the slides umbrella-parasol. A simulacra made of some of the structural segments of the towers might be afloat where the two centers of the towers used to be. The remaining floors, 40 to 50, are for the transnational activities in financial, economic, environmental, social equity fields of endeavor.[Image: Arcosanti Graphics & text: Paolo Soleri]last_img read more

Rep Griffins plan to save taxpayer money on prison health care signed

first_img23May Rep. Griffin’s plan to save taxpayer money on prison health care signed into law Categories: Griffin News State Rep. Beth Griffin, right, attends a bill-signing ceremony Wednesday with Gov. Gretchen Whitmer and Lt. Gov. Garlin Gilchrist.State Rep. Beth Griffin’s plan to reduce the amount of public tax dollars spent on prison health care while continuing to protect public safety has been signed into law by the governor.Griffin, of Mattawan, said chronically ill and aging prisoners often have health care costs several times higher than the average inmate. It’s a growing concern in Michigan, where nearly one in four inmates is 50 or older with the average age continuing to rise. Health care already takes up 15 percent of the prison system’s budget, costing taxpayers roughly $300 million.“I’m always looking for ways to help our state government operate more efficiently and effectively,” Griffin said. “This is a responsible reform that saves taxpayer dollars without jeopardizing public safety in any way.”Griffin said the new law permits some inmates with severe and chronic physical or mental disabilities to complete their sentences at a medical facility rather than inside a prison, if approved by a parole board. It does not allow early release of inmates.The goal is to qualify inmates transferred to health care facilities for Medicaid, which would translate to a net savings for taxpayers.Only inmates classified by professionals as not posing a risk to public safety would be allowed to relocate. Prosecutors and victims could appeal decisions, and inmates convicted of first-degree murder, criminal sexual conduct in the first degree or any other crime resulting in a life sentence would automatically be ineligible for the program – meaning they stay behind bars.An initial projection from the Department of Corrections estimates roughly 20 to 40 prisoners could potentially be eligible for the program. The number could grow over time as the prison population ages.House Bills 4129-32, now Public Acts 13-16 of 2019, received overwhelming support in the House and Senate.###last_img read more

Video monitoring specialist Bridge Technologies ha

first_imgVideo monitoring specialist Bridge Technologies has signed up SHM Broadcast to resell its products in the German market.In addition to solutions for cable, terrestrial, and satellite infrastructures, SHM Broadcast will offer all the OTT monitoring tools included in the latest VideoBRIDGE probes, as well as the new versions of the microVB system for monitoring OTT and TV everywhere services.last_img

The sociopath hides his or her difference After l

first_img The sociopath hides his or her difference. After letting it show a time or two—and probably being punished by a parent as a result—the sociopath covers up the truth and keeps it covered. But the reason for hiding it is not embarrassment (the sociopath doesn’t feel embarrassment), but because it hinders him from getting what he want. Sociopaths understand that they are different from normal people and learn to mimic normal behavior. This mimicry has a purpose: It gets the sociopath what he or she wants. Since sociopaths have no empathy for others, making use of normal people feels just fine to them. Likewise, they feel no remorse. Because they lack an internal feedback system, sociopaths are excellent liars. For example, they can often pass lie detector tests, since those tests register the effects of our internal feedback system, which they don’t have. Empathy, as viewed by the sociopath, is a weakness, and he considers himself superior, because he isn’t burdened by it. By Paul Rosenberg Here’s the bad news: Predators walk among us, and they are indistinguishable from normal people. These differently wired humans have a predatory advantage, and they use it. This is not a plot from a scary movie; this is real. I am deadly serious about this, though by the end of this column, I will also explain why there is also good news. These predators are called sociopaths (psychopaths in the clinical literature). They rather seldom damage our bodies, but they make careers out of bleeding our souls. I’m not trying to be dramatic, by the way. I was holding this subject for the next issue of my subscription newsletter, but the more I worked on it, the more I was convinced that I should publish some key points ahead of schedule. This is important. So, before we go any further, I’d like to give you two essential facts that will allow you to protect yourself from sociopaths. If you can remember these, you’ll avoid a lot of pain: 1 in 50 people is a predator. At least 2% of the overall populace are sociopaths, and some estimates are double that. Perhaps 75% of them are male, though no one knows why. That means that at least every thirty-third man is a sociopath, and every hundredth woman. Most of us have a feeling that everyone has some goodness in them. This is generally a useful feeling, but it’s only true for 49 out of 50 humans. That last one is a predator without a conscience. I don’t like the sound of that any better than you do, but it has been proven over and over and over. We need to face the facts, and we cannot treat these people like we do everyone else. You must pay attention to inauthentic emotions. Sociopaths have a “tell” that gives them away: Emotions that are not quite right. They don’t have much in the way of positive emotions themselves, so they fake them. But they can never fake them completely. Authentic expressions of emotions are very complex, involving dozens of muscles, increased or decreased blood flow and pressure, pulse rate, posture, tone of voice, and more. Normal people are deeply familiar with these complicated arrangements and innately understand their patterns. The sociopath, on the other hand, doesn’t feel them and can’t grasp their patterns. He or she must mimic them. But because of the great complexity involved, the sociopath can never mimic them terribly well. So, you must notice inauthentic emotions, remember them, and not ignore them in an effort to be nice. The How and the Why There are a lot of things to understand about sociopaths, and we can’t cover them all in one column, but I will give you the basics, which are these: Sociopaths have a profound lack of empathy for the feelings of others. They lack the internal feedback system by which normal people monitor themselves. (Most people call this “conscience,” which is probably as useful a term as any.) Sociopaths do not have this and don’t feel bad about abusing other people. It’s not that they feel bad and ignore it—they don’t feel it at all. A sociopath is likely to maintain a group of people who believe whole-heartedly that he is a good, kind, honest person. He’ll work in calculated ways to create and maintain that opinion in them. Here is what Hervey Cleckley wrote about sociopaths in his classic text on the subject, The Mask of Sanity: Beauty and ugliness, except in a very superficial sense; goodness, evil, love, horror and humor have no actual meaning, no power to move him. Now we come to the question of why sociopaths are this way, and we do have some answers. Recent brain scans indicate that sociopaths have unusually small amygdalae (the part of the brain associated with emotional reactions, decisionmaking, and memory processing). A region of the brain’s frontal cortex, called the orbitofrontal cortex, seems problematic as well. This region, which communicates with the amygdala, is also involved with decision making. So, the cause of sociopathy is almost certainly organic. Someday it should be curable with genetic engineering, but for now, there is no cure at all. That means that you have zero chance of talking a sociopath into behaving well. Trying to repair a sociopath tells him that you’re a ripe sucker, and nothing more. He’ll play along, tell you what you want to hear, fake the emotions he thinks you’ll respond to, and bleed you dry, emotionally and physically. And he’ll never feel a moment’s remorse as you finally contemplate suicide. Yes, I know this is dark stuff, but it’s better to be forewarned than to learn through harsh experience. Why This Is Actually Good News Considering that sociopaths make up 2% of the total population, and considering that a sociopath is responsible for several times more damage than the average person (I’d guess at least five to ten times as much), then… training people to recognize and avoid sociopaths would eliminate a serious percentage of human suffering. And it gets better. Aside from natural causes like diseases, the number-one source of pain on Earth is political systems. For today I’ll pass up the argument of whether states are necessary or not; instead, I’d like to make a simpler point: Governments, like all hierarchies, are havens for sociopaths. And governments have, over the last century, killed approximately 260 million people. (See Death by Government, by R.J. Rummel.) So, what would happen if millions of people, because they were able to recognize sociopaths, stopped empowering and obeying them? I’m trying to think of any single thing that would eliminate human suffering better than sociopath recognition, and I’m not coming up with much. Furthermore, it would be easy: websites, billboards, tiny radio and TV ads, flyers, handouts, and just about anything else could be used. The concepts are simple and potent, and the motivation to avoid pain is inherent in human nature. For far less than corporate charities spend, something like this would change the world… more, better, and faster. Something to think about. A Free-Man’s Take is written by adventure capitalist, author, and freedom advocate Paul Rosenberg. You can get much more from Paul in his unique monthly newsletter, Free-Man’s Perspective.last_img read more

An intellectual talk about racism I dont like th

first_img An intellectual talk about racism. I don’t like the term diversity. I think from now on, instead of diversity, they should just call it what it is: bigotry! —Craig We’re in Uncharted Territory Throughout the 1920s, the Federal Reserve’s easy-money policies helped create an enormous stock market bubble. In August 1929, the Fed raised interest rates and effectively ended the easy credit. Only a few months later, the bubble burst on Black Tuesday. The Dow lost over 12% that day. It was the most devastating stock market crash in the US up to that point. It also signaled the beginning of the Great Depression. Fast forward to today… The economy has been on life support since the 2008 financial crisis. The Fed has pumped it up with unprecedented amounts of “stimulus.” This has created enormous distortions and misallocations of capital that need to be flushed. Think of the trillions of dollars in money-printing programs—euphemistically called quantitative easing (QE) 1, 2, and 3. Meanwhile, with zero and even negative interest rates in many countries, rates are the lowest they’ve been in 5,000 years of recorded human history. This is not hyperbole. We’re really in uncharted territory. (Interest rates were never lower than 6% in ancient Greece and ranged from 4% to over 12% in ancient Rome.) The too-big-to-fail banks are even bigger than they were in 2008. They have more derivatives, and they’re much more dangerous. Allegedly, the Fed has been taking these actions to save the economy. In truth, it’s warped the economy far more drastically than it did in the ’20s. I expect the resulting crash to be that much bigger. Good one. —Judy NEVER Before Seen: The Aurora Borealis of Trading The Biggest Threat to Your Financial Well-Being The mainstream “fake news” media endlessly praises the Fed. It portrays Fed employees as a bunch of selfless, benign bureaucrats trying to save the economy. In reality, the Fed is the primary cause of most of the harmful distortions in the economy. You can blame the Fed for… Unlimited money printing Artificially low interest rates The boom/bust cycle Bailout funds to prop up “too-big-to-fail” institutions The War on Cash Cronyism in the financial industry Various asset bubbles… just to name a few. If you ask me, the Fed is the biggest threat to your financial well-being. Period. Today, That Threat May Be Imminent Last December, the Fed raised interest rates to their highest levels since the 2008 crash. That could help prick the massive bubble in the stock and bond markets. But the threat goes beyond that. Even a small rate increase could also be lethal for the US budget, which is built on credit. In other words, economic depression and currency inflation (perhaps hyperinflation) are very much in the cards. These things rarely lead to anything but bigger government, less freedom, and shrinking prosperity. Sometimes, they lead to much worse. Fortunately, you don’t need to be hostage to what’s coming. You can take a few steps today to prepare for the worst. To help you get started, our team just put together the Ultimate Crisis Playbook. With 109 pages full of tactical steps from every guru across our business, this market crash guide is designed not just to help you protect your wealth in the months ahead… but also to prosper. You can download it for free right here. Regards, Nick Giambruno Editor, Crisis Investing Reader Mailbag Today, readers weigh in on John Hunt’s recent essay on racism: Well done, but only educated people will read through it, get to the truth of the issue, and subscribe. Unfortunately, those who benefit and those who use it to their advantage don’t want to recognize that they are being used. —Joyce The Aurora Borealis, or “Northern Lights,” happens when solar particles rip through the Earth’s geomagnetic field and smash into gas atoms. Something similar exists in the stock market… It’s a powerful anomaly called “Quantum.” It appears when 3 major forces collide. As a result, the laws of risk and reward reverse. And the gains that are generated are incredible—both in their return and the speed in which they’re created.GDX: 129% in 3 hoursSONC: 400% in 18 hoursSTRA: 1,285% in 2 daysClick here to continue reading… (and to see where this anomaly will appear next). Justin’s note: Today, I’m sharing an important essay from Crisis Investing editor Nick Giambruno. Below, he explains the main cause for the harmful distortions in today’s economy—and why things will only get worse from here.Fortunately, we just put the finishing touches on the ultimate crisis report to help you protect yourself (and thrive) in the months ahead. Read on to learn more… By Nick Giambruno, editor, Crisis Investing You may recall the international spectacle Alan Greenspan sparked in 1996. In an otherwise dull and forgettable speech, Greenspan, the Federal Reserve chairman at the time, said the now-famous phrase “irrational exuberance.” Investors thought Greenspan meant the Fed was about to raise interest rates. Of course, Greenspan didn’t say the Fed would raise rates. Nor did he intend to signal that. Nonetheless, investors quickly panicked. US markets were closed at the time, but stocks in Japan and Hong Kong dropped 3%. The German stock market fell 4%. When trading started in the US the next day, the market opened down 2%. Billions of dollars of wealth vanished in 16 hours… all because one man said two words. That’s an absurd amount of power for one person to have. It’s also a shameful testament about the economy. It’s based more on the Fed’s shenanigans than actual production. After the US president, the Fed chair is the most powerful person on the planet. By simply saying the right words, the Fed can create or destroy trillions of dollars of wealth in both the US and abroad. Recommended Linkcenter_img “This Wednesday, I’m revealing my big crypto prediction for 2018” — Last year, Teeka’s crypto prediction could have made you rare and extraordinary gains of 696%… 1,140%… and even 14,354% — in as little as 6 months. This Wednesday, he’s revealing a new shocking prediction for 2018 in a free emergency broadcast. Click here for details. Recommended Link — Mr. Hunt, I’m not sure what world you live in, but your views and perspectives on racism vastly differ from mine. Perhaps you should stick to investments and the financial markets. —LarryIf you have any questions or suggestions for the Dispatch, send them to us right here. In Case You Missed It… Our colleague Teeka Tiwari, one of the world’s top cryptocurrency experts, has an urgent message… “I just returned from a three-month, international cryptocurrency investigation. Based on what I found, I believe we’re on the cusp of a ‘Second Boom.’” And he’s explaining all the details in a live crypto emergency broadcast on Wednesday, March 14. Teeka’s never shared this information in an in-depth presentation. To sign up for this event, click here.last_img read more

One of the largest airports in the country has bee

first_imgOne of the largest airports in the country has been branded one of the worst for accessibility, after it failed to consult with disabled people about how it could improve its services.Manchester Airport is one of just four in the UK that were said in the Civil Aviation Authority’s (CAA) annual review to be providing “poor” services to disabled passengers.Two of the others, Exeter and East Midlands, were also criticised for their failure to carry out any consultation at all with groups representing disabled people.The fourth “poor” airport, Heathrow, was criticised over the quality of its assistance service, with three-fifths of passengers who took part in a survey rating it as “unsatisfactory”.In its second annual review of accessibility at UK airports, CAA found six “very good” airports, 20 “good” and four that were categorised as “poor”*.It also found the number of disabled passengers requesting extra help at airports rose from 2.7 million in 2015 to more than three million in 2016 – an increase of more than two-thirds since 2010 – with satisfaction levels with assistance services consistently showing well over 80 per cent.Disabled passengers are entitled to free assistance when traveling by air under European Union regulations, and CAA is the regulatory body that monitors the quality of this assistance.The government is due to consult on how to improve access to air travel this autumn, while there will also be a consultation on plans to improve access across the public transport network.Those airports that rated well in the CAA report were those that “regularly consulted with people that use the assistance service”, whose staff were “regularly praised by passengers for their understanding and patience”, and where assistance was “efficient and well organised”, leading to minimal delays.Among those categorised as “very good”, Norwich had “created excellent partnerships with local disability organisations”, Glasgow Prestwick “hosted successful familiarisation and feedback events with charities representing people with sensory impairments and with learning disabilities”, while staff at Inverness Airport attended “numerous” local access panels.But CAA said it was “unacceptable” for an airport the size of Manchester to fail to carry out any consultation at all with disability organisations in 2016-17, although it said discussions about improving this situation had been “constructive”.Members of Greater Manchester Coalition of Disabled People (GMCDP) this week delivered a “damning” description of travelling through Manchester Airport. One member had to make their own way to the departure gate after arriving early in the morning for their flight and finding no assistance staff on duty.Another said there were never enough staff on duty or wheelchairs available.Some staff were said to be “kind, courteous and understanding” but many were said to treat disabled people as “little better than cattle”.Brian Hilton, GMCDP’s digital campaigns officer, who spoke this week to several members about their experiences of the airport, told Disability News Service: “Disabled people are paying the same amount for flights as everyone else but are getting an inferior service at Manchester Airport.“If Manchester Airport is serious about promoting itself as the gateway to the north it needs to up its game. It needs to talk to and listen to disabled people.“It needs to implement practices and procedures that ensure disabled people travel safely and in comfort and are not made to feel like second-class citizens.”GMCDP is the longest-established disabled people’s organisation (DPO) in the north-west of England, but Hilton said: “We have never had any contact from Manchester Airport saying ‘we would like to consult with you and your members.’“There is a huge potential for joint working and making things better.“It’s not that they are knocking on a closed door, they are knocking on an open door. We are willing to work with the airport.“We want to see Manchester Airport as a beacon for accessibility.“That can be achieved but there needs to be some will shown, some proactive action.”In May, GMCDP published its manifesto for the Greater Manchester mayoral election, which called on the airport to introduce DPO-led customer service training, and to carry out regular access audits, which Hilton said should also be done in conjunction with DPOs.A spokesman for Manchester Airport said the airport’s contractor OCS had recently recruited more than 100 new customer services staff to work with disabled passengers, and their initial training had included “hidden disability training”.A new contract with OCS should cut response and waiting times, he said.He said in a statement: “We acknowledge the CAA’s findings and comments relating to consultation with disability organisations.“As referred to by the report, this is an area we have already taken steps to address.“Starting this financial year, we have launched a disability engagement programme, with the first quarterly forum being held last month.”Organisations who have joined the forum include the disability charities Stomawise, Support Dogs, Guide Dogs, Queen Elizabeth’s Foundation for Disabled People, Alzheimer’s Society, the Motor Neurone Disease Association, Action on Hearing Loss and MS Society.The airport also plans a “Disability Expo” in November, which will “showcase” how it supports disabled passengers.He said: “We are confident that this work, coupled with the ongoing representation of a disability organisation [Disability Stockport] on our consultative committee, will lead to significant improvement in this area.“Ensuring those who need assistance enjoy a positive experience at our airport is both a priority of ours and the organisations contracted to provide such services on our behalf.“We regularly review customer satisfaction surveys relating to this area, with the majority of customers currently rating us very good.“However, we constantly strive to deliver a better experience for all our passengers and will continue to do so in the months ahead.”He added: “We have now started the journey of engagement to develop the service and improved accessibility. We’d welcome contact with GMCDP.”Meanwhile, an investigation by the Trailblazers network of young disabled campaigners – part of Muscular Dystrophy UK – has exposed the “shocking” number of UK hotels that fail to provide hoists.Hoists allow wheelchair-users to transfer into a bed or to use bathroom facilities when they cannot transfer independently, but almost 80 per cent of the 103 young disabled people who took part in the survey said they had been unable to go on holiday in the past five years because of the lack of hoist facilities in hotels.A further mystery shopping exercise found only one in 20 hotels offered the use of a free hoist.Lucy Watts, a Trailblazers member from Essex, said: “I haven’t stayed away from home since losing the ability to transfer and I’ve been unable to stay overnight purely because of the hoist issue.“Hotels having hoists would mean I’d be able to take trips away.”She added: “Disabled people face enough barriers in life. We shouldn’t be prevented from enjoying trips away because hotels won’t always make the effort to be fully accessible and inclusive.”*CAA said the results could not be compared with its first annual review as the categories have changedlast_img read more

Why the Next Technological Revolution in Alternative Meat Is Chicken

first_img Brian Kateman Image credit: Juhari Muhade | Getty Images Cofounder and President of the Reducetarian Foundation July 2, 2019 Learn from renowned serial entrepreneur David Meltzer how to find your frequency in order to stand out from your competitors and build a brand that is authentic, lasting and impactful. Next Article –shares 4 min read Guest Writer Opinions expressed by Entrepreneur contributors are their own. Add to Queue Why the Next Technological Revolution in Alternative Meat Is Chicken Meat Industry Fireside Chat | July 25: Three Surprising Ways to Build Your Brand Backyard barbecue season is just around the corner, and it’s clear this has been a tremendous year for plant-based meat. Several months ago, Beyond Meat teamed up with Carl’s Jr. and Del Taco to offer its plant-based burgers and crumbles. More recently, Burger King announced the nationwide rollout of a Whopper made with a vegetarian patty from the startup Impossible Foods. These and other leading plant-based meat-alternative companies bet big on beef, and boy, did it paid off. But some companies already have their eyes set on the next technological revolution in meat: chicken.While beef alternatives may be getting most of the buzz lately, animal-based chicken is the uncontested champion of American plates. Beginning in 1992, for the first time in recorded history, chicken became more popular than beef in the U.S. According to data from the U.S. Department of Agriculture, in 2018, Americans ate a record 93 pounds of chicken per person, and roughly the same amount is projected for 2019 — more than 50 percent of beef consumption.Why the meteoric rise in chicken consumption? Many factors play a role, but two stand out. Firstly, in one survey, 88 percent of consumers said they think that chicken is healthier than beef or pork (although recent evidence suggests this may not be true). Secondly, price: according to Food and Agricultural Economist Jayson Lusk, “In the early 1970s, a pound of beef was about 2.5 times more expensive than a pound of chicken, and this figure trended upward over time. Today, beef is over four times more expensive than chicken.”To meet this demand, food companies have begun to roll out chicken alternatives on the market. Perdue Foods in partnership with Better Meat Co. is touting a line of chicken products that blend chicken and vegetables — a mix of cauliflower and chickpeas formed into chicken nuggets, tenders and patties — that will be coming to retailers nationwide in September. Tyson Foods is promoting the fact that it will begin selling nuggets made from pea protein at grocery stores this summer. A new entrant into the foray, Rebellyous Foods, is aiming to corner the meat-free fried chicken market by bringing plant-based meat’s costs down.In the U.K., KFC has just announced it is trialing a vegan chicken burger in stores across England. The Imposter Burger features a fillet made from Quorn, coated in the Colonel’s Original Recipe herbs and spices. It proved so popular that it sold out in just a couple of days.While it is true that there are many plant-based chicken products already on the market, they have arguably fallen behind the unprecedented innovation we’ve seen in its red meat counterpart. Indeed, the investment into research and development of comparable chicken products seems to have been far outweighed by the likes of red meat products such as the Beyond Burger and Impossible Burger. These recent developments, however, could signal a change. And there is a lot at stake to getting plant-based chicken right.Nine out of every 10 land animals killed for meat are chickens. The overwhelming majority are raised on factory farms, where they are confined in dark, warehouse-like buildings, each packed with as many as tens of thousands of chickens. Such intensive confinement breeds filth and disease, and many suffer from serious health problems as a result, including chronic respiratory illnesses and bacterial infections. (McDonald’s for example still sources chickens who’ve been bred to grow so large, so fast that many cannot even walk without pain. However, Burger King, Subway, Jack in the Box and more than 100 other food companies have committed to phasing out this abuse.) Moreover, poultry farming is one of the leading causes of climate change, as production methods inherently spew carbon dioxide, nitrous oxide, methane and other greenhouse gas emissions into the atmosphere. And our culinary love affair with chicken may help explain why only one in 10 adults get enough fruits or vegetables.The reality is that most consumers don’t choose food based on these ethical, environmental and health issues. Rather, they decide what to eat based on price, taste and convenience. Therefore, the only way we’ll solve these problems is if companies are able to develop chicken alternatives that are just as inexpensive, delicious and common place as animal-based meat, much like the Impossible Burger and the Beyond Burger have already achieved. By investing more research and development into plant-based chicken products, it may not be long before more consumers are squawking for more of them. By investing more research and development into plant-based chicken products, it may not be long before consumers are squawking for more of them. Enroll Now for $5last_img read more

Ecommerce Shop Fancy Just Laid Off a Third of Its Staff

first_img 4 min read Ecommerce Shop Fancy Just Laid Off a Third of Its Staff This story originally appeared on Business Insider Add to Queue Layoffs Free Webinar | July 31: Secrets to Running a Successful Family Business Learn how to successfully navigate family business dynamics and build businesses that excel. November 14, 2014 Joe Einhorn’s e-commerce shop Fancy, which was rumored to be in ~$1 billion acquisition talks with eBay in September, has laid off an estimated one-third of its staff, multiple sources tell Business Insider.A few layoffs were scattered throughout the summer, two sources say, with the largest round occurring on or about September 30. There, 10-15 staffers across different departments were handed paperwork by the company’s lawyer, Andrew Tuch. COO Michael Silverman only said a sentence or two, then dismissed the group.”Just fired 16 employees in one day with no warning and no explanation,” an anonymous reviewer wrote on Glassdoor in October. A number of Glassdoor reviewers allege that the company has a tendency to fire employees just before their stock options vest. Two former Fancy employees estimate that one-third of the company was cut that day, scaling a team of 45 US employees last year down to about 15 or 20 now. Another person who confirmed the layoffs thinks the one-third estimate is too high and estimates the the company had about 80 employees world-wide during its prime.Two executives have departed in recent months: Creative Director Jake Frey and General Merchandising Director Lee Assoulin. One source says the layoffs struck shortly after a board meeting. Roles cut include buyers, sales processors and business development.The reason for the layoffs vary depending on whom you ask. Those who are disgruntled feel the company spent too much cash and is in desperate need of a lifeboat. “If I had to speculate, [the layoffs occurred] because Fancy isn’t making enough money to support the business and pay salaries, and the investment money from last year (about $60 million) is pretty much all gone,” one person says.A SEC filing spotted by AllThingsD’s Jason Del Rey showed that executives from Fancy took about $20 million off the table during the company’s last fundraise. A source familiar with the company’s thinking admits that the filing looked bad, but says the money was distributed among a dozen early supporters of the company. “That money was distributed between 10-12 people who were part of the beginning fundraising,” this person says. “It wasn’t getting anyone super rich.” This person says the company is currently raising a new round, but wasn’t sure of the valuation.In September, Bloomberg reported that Fancy was in talks to get acquired by eBay for ~ $1 billion. One former staffer guessed layoffs might have had something to do with that.While Fancy did meet with eBay’s Marketplaces Business Unit President, Devin Wenig, a source familiar with the talks says no buyout price was ever discussed and was skeptical acquisition talks with eBay had ever occurred. This person says it was a typical business meeting, similar to one Fancy had with Twitter, which resulted in a Twitter Commerce partnership. Fancy recently pivoted its business from being a first-party merchant (storing inventory and shipping it to customers) to a third party merchant, where other businesses promote, sell and ship their own items to Fancy’s users. “What they were doing with first-party buying was — well, it was working in that it was making revenue and blah, blah, blah — but it wasn’t getting the full social shopping experience, where a user could look at whatever they wanted and get it in the same day,” a source familiar with the company’s thinking says. “When things started getting slow, Fancy had to pivot and make this third-party storefront. It’s an incredible tool. Imagine going on Shopify and buying everyone on there all in one place.”The pivot, this person says, is what forced the company to downsize.”It is clear as day what was happening with Fancy,” says the source. “We went from first party to third party merchants, so there was a group of people in charge of that. Fancy tried to repurpose as many of those people into other roles as possible but at the end of the day, it’s a startup and when it pivots it pivots…[Layoffs are] always unfortunate but at the end of the day, Fancy is a startup that is still young and agile.”Fancy COO Michael Silverman and CEO Joe Einhorn did not return requests for comment. Next Article Alyson Shontell –shares Register Now »last_img read more

Banks Tech Companies Move on From Bitcoin to Blockchain

first_img As a debate raged across the Internet Monday over whether the mysterious founder of the bitcoin digital currency had finally been identified, executives at a major bitcoin conference in New York had a simple message: we’ve moved on.That’s because bitcoin, the digital currency, has largely been supplanted by blockchain, the technology that underlies it, as the main interest of investors, technology companies and financial institutions.”If there is a 100 percent opportunity in the blockchain, bitcoin, or the currency, is only 1 percent of it,” said Jerry Cuomo, vice president, Blockchain Technologies at International Business Machines Corp. “So there is a whole 99 percent that has broad applications across the broad industries.”Over the past year numerous Wall Street firms, led by Goldman Sachs, have declared their commitment to pursuing blockchain as a potential revolutionary technology for tracking and clearing financial transactions.The blockchain technology works by creating permanent, public “ledgers” of all transactions that could potentially replace complicated clearing and settlement systems with one simple ledger.Still, bitcoin is by far the largest implementation of blockchain technology and there is considerable debate as to whether one can truly develop without the other.”Bitcoin is still the only blockchain-enabled, cross-border large scale, provable application that’s actually in production,” said Joseph Guastella, a principal at Deloitte Consulting in New York. “Bitcoin as a currency may not be as relevant as it was in many ways, but it actually is relevant as a proof case for the blockchain technology.”Bitcoins are created through a “mining” process, in which specialized computers solve complex math problems in exchange for bitcoins. One bitcoin is equivalent to $444.75 late on Monday and trade on various exchanges around the world.But bitcoin transaction volume has been in decline over the past six months amid a bitter split over technical changes in the protocol that are needed to increase the capacity of the system that produces them. Because the cryptocurrency has no formal governance, it relies on a core group of developers for direction – and they are sharply divided over the changes.But that debate was of relatively little concern to the Blockchain enthusiasts gathered in New York.Australian tech entrepreneur Craig Wright identified himself on Monday as the creator of controversial digital currency bitcoin.”It’s irrelevant because his announcement doesn’t solve a problem or resolve a conflict,” said Bharat Solanki, managing director at Cambrian Consulting in New York.”It probably helps to determine the origins of bitcoin but only for recognition,” Solanki said.For Naoki Taniguchi, a global innovation expert at The Bank of Tokyo-Mitsubishi UFJ Ltd. in San Francisco, he does not really care about who created bitcoin.”It’s all about the blockchain,” he said.(Reporting by Gertrude Chavez-Dreyfuss; Editing by Jonathan Weber, Bernard Orr) 2019 Entrepreneur 360 List Bitcoin The only list that measures privately-held company performance across multiple dimensions—not just revenue. –shares Next Article 3 min read This story originally appeared on Reuterscenter_img Banks, Tech Companies Move on From Bitcoin to Blockchain Add to Queue Reuters Image credit: REUTERS/BENOIT TESSIER/FILE PHOTO May 3, 2016 Apply Now »last_img read more

Supreme Court Weighs TruthInLabeling Issue In Case Involving Juice Product

first_img This is part of the KHN Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription. The makers of a pomegranate juice called Pom Wonderful ask the court to rule that Coca-Cola is falsely labeling its Pomegranate Blueberry juice that is 99.4 percent apple and grape juice.Los Angeles Times: Supreme Court Seems Inclined To Bolster Truth-In-Labeling LawsIn a case that could strengthen truth-in-labeling laws, Supreme Court justices on Monday voiced deep skepticism about Coca-Cola’s Pomegranate Blueberry juice that is 99.4% apple and grape juice, saying the name would probably fool most consumers, including themselves. The high court is hearing an appeal from Stewart and Lynda Resnick of Los Angeles, makers of a rival pomegranate juice called Pom Wonderful, who complained that the name of the Coca-Cola product, sold under the Minute Maid brand, is false and misleading. … At issue is whether federal law permits selling a product with a name or a label that is almost sure to mislead consumers, and how much latitude manufacturers have in marketing (Savage, 4/21).The Wall Street Journal: Justices Skeptical Of Coke’s Pomegranate Juice LabelLos Angeles-based Pom, which sells juices and juice blends with high content of costly pomegranate juice, claims that Coke is misleading consumers with a Minute Maid product it calls Pomegranate Blueberry Blend of Five Juices. The product, which contains about 0.5% of pomegranate and blueberry juices, highlights the words Pomegranate Blueberry, features a pomegranate and blueberry on its label, and is colored a bluish-purple, altering the natural hue of the less pricey apple and grape juices that make up more than 99% of the beverage (Bravin, 4/21).The high court will also consider a case Tuesday involving abortion and free speech – Politico: Abortion At Heart Of Ohio Speech CaseThe Supreme Court will consider Tuesday whether an anti-abortion group can challenge an Ohio law that could have restricted it from publicly accusing a political candidate of voting for taxpayer-funded abortions in Obamacare. The justices aren’t likely to decide whether the law chills free speech—although Susan B. Anthony List and even the Ohio attorney general say that it does. They’re instead being asked to decide whether SBA List has standing to challenge the law since the group was never prosecuted under it (Winfield Cunningham, 4/22). Supreme Court Weighs Truth-In-Labeling Issue In Case Involving Juice Productlast_img read more

New blood test for pediatric brain tumor patients offers safer approach than

first_imgReviewed by James Ives, M.Psych. (Editor)Oct 16 2018A new blood test for children with brain tumors offers a safer approach than surgical biopsies and may allow doctors to measure the effectiveness of treatment even before changes are identified on scans, according to research led by UCSF Benioff Children’s Hospitals and Children’s National Health System.Unlike a standard brain biopsy, which entails drilling a small hole through the skull to extract a sample of the tumor, the so-called liquid biopsy is minimally invasive and involves analyzing molecules in the blood or the cerebrospinal fluid, which bathes the brain and spinal cord, for the tumor’s specific genetic signature. The study appears in Clinical Cancer Research on Oct. 15, 2018.In the study, 48 children with a high-grade brain tumor called diffuse midline glioma (DMG) underwent liquid biopsies using plasma from blood draws and cerebrospinal fluid from spinal punctures. The investigators looked for circulating tumor DNA in these samples, using a highly sensitive technique called digital droplet polymerase chain reaction that precisely counts individual DNA molecules.They identified a driver mutation called H3K27M in 42 of the 48 patients, a level comparable to that found using standard biopsy.Among the 12 children who had undergone liquid biopsy before and after radiation — standard treatment for many types of brain tumors — the investigators discovered that the circulating tumor DNA had decreased significantly, indicating the tumor had receded. This reduction was later confirmed by MRI in 10 of the 12 patients.”Most diffuse midline gliomas can be surgically biopsied, but this is frequently not carried out at recurrence, due to risk,” said co-senior author Sabine Mueller, MD, PhD, a pediatric neuro-oncologist at UCSF Benioff Children’s Hospital San Francisco. “Consequently, physicians rely on clinical exams and MRIs to assess response to therapy, although both of these methods are limited in sensitivity and specificity.”Subtle tumor growth may not be evident on MRI, leading to under-diagnosis in its earliest phase. When tumor recession is detected on MRI, it is a clear indicator that the child’s treatment is working, but radiation and certain other treatments can cause inflammation that masquerades as growth making it difficult to assess the impact of treatment.Brain tumors are the most deadly form of childhood cancer, according to a 2016 report from the Centers for Disease Control and Prevention. Close to 30 percent of childhood cancer deaths are now attributed to brain tumors. Unlike treatments for childhood leukemia and lymphoma, which have improved steadily for decades, advances have been modest for some types of pediatric brain tumors.First Time Technique Used in Pediatric Brain Tumor TrialRelated StoriesMercy Medical Center adds O-arm imaging system to improve spinal surgery resultsAn active brain and body associated with reduced risk of dementiaWearing a hearing aid may mitigate dementia riskAt a time when neuro-oncologists are reimagining treatment of high-grade and refractory brain tumors, and turning to targeted therapies that match a tumor’s mutations, there is a heightened need to monitor tumor growth, evolution and response to treatment, said co-senior author Javad Nazarian, PhD, of Children’s National Health System and George Washington University School of Medicine and Health Sciences in Washington, D.C.”Selecting appropriate, tumor-specific treatments requires the ability to frequently monitor progression of the tumor and the genetic changes that evolve over time,” Nazarian said. “Circulating tumor DNA is increasingly used for disease monitoring in adult cancers, including the adult brain tumor glioblastoma, and melanoma, lung, breast and colon cancers. However, this is the first use of the technique in a pediatric brain tumor population in a clinical trial.”Bringing emerging technologies to the clinic will allow us to achieve precision medicine for treating the most vulnerable patient populations,” he said.The researchers further looked at a subset of patients with an especially virulent form of DMG called diffuse intrinsic pontine glioma (DIPG). These patients were enrolled in a trial conducted by the Pacific Pediatric Neuro-Oncology Consortium, led by Mueller. Looking only at plasma samples — which are less enriched than cerebrospinal fluid with circulating tumor in DNA — the researchers detected a type of mutation at diagnosis in 16 of the 20 samples that had been identified at standard biopsy.Following tumor progression, nine of the children with DIPG underwent precision therapy with drugs that matched the mutations identified with liquid biopsy. The treatment led to a drop in circulating tumor DNA, indicating reduced tumor volume, which was later confirmed by MRI.Liquid Biopsy Offers Quick Answers to Treatment Effectiveness”These results are encouraging,” said Mueller. “Liquid biopsies have the potential to tell us if a patient is a candidate for a targeted therapy and if that therapy is working in real time.”Eventually, targeted therapies will lose effectiveness as the tumor ‘learns’ new ways to evade treatment, and new mutations and alterations will drive its growth. Over time, we anticipate that new targeted therapies will emerge that will further slow disease progression.” Source:https://www.ucsf.edu/news/2018/10/411986/blood-test-biopsy-kids-brain-tumors-simple-safe-way-see-if-treatment-workinglast_img read more

Sugary drinks may be addictive and are harmful to health study suggests

first_imgReviewed by James Ives, M.Psych. (Editor)Nov 21 2018Deprived of beverages, regular drinkers reported headaches, cravingsJust as we might have guessed, those tasty, sugar-sweetened beverages that increase risk of diabetes and other chronic diseases may actually be addictive. Youth between 13 and 18 years of age who were deprived of sugary drinks for just three days reported headaches, cravings and other withdrawal symptoms, according to a University of California study with researchers from both the Davis and Berkeley campuses.All 25 participants in this exploratory study reported normally consuming at least three sugar-sweetened beverages a day before the study and were told they were participating in a study exploring “how soda affects teenagers’ health.”The youths reported the following specific symptoms during the three-day period of cessation from sugary drinks: increased headaches, decreased motivation to do work, lack of contentment and ability to concentrate, cravings for sugary drinks, and lower ratings of overall wellbeing.The findings were published in an article, “Potentially addictive properties of sugar-sweetened beverages among adolescents,” appearing in the journal Appetite.”An abundance of research points to sugary drinks as contributing to a number of chronic diseases. Our findings — that these drinks may have addictive properties — make their ubiquitous availability and advertising to youth even more concerning for public health,” said Jennifer Falbe, assistant professor in the Department of Human Ecology in the College of Agricultural and Environmental Sciences at UC Davis and the lead author of the article.The teens, all overweight, were instructed to consume their normal beverages for five days, then, for three days afterward, to consume only water or plain milk. They were reimbursed for travel and received up to $160 for participation.Related StoriesDiabetes patients experiencing empathy from PCPs have beneficial long-term clinical outcomesTAU’s new Translational Medical Research Center acquires MILabs’ VECTor PET/SPECT/CTResearch sheds light on sun-induced DNA damage and repairParticipants, a diverse population living in and around the San Francisco Bay Area, kept beverage journals and reported in to researchers several times during the study. Three quarters of the participants were female. They also submitted saliva samples to test for caffeine intake, which could affect results. Most of the participants were not high caffeine consumers before the study, reducing the likelihood that participants were just suffering from caffeine withdrawal, an established disorder, rather than also reduced sugar intake.Among nine participants, there were some lapses in compliance, usually due to drinking flavored milk instead of plain milk.The study noted that results were consistent with previous research that has reported the addictive potential for sugar, a relatively new but burgeoning area with parallels to substance abuse. Additionally, researchers said, the study was needed because sugar-sweetened beverage consumption by teens had increased five-fold since the 1950s, and adolescence is a time for increased susceptibility to addiction. Young people, the report said, consume the largest amounts of sugary beverages and have experienced the greatest relative gains in obesity in the past several decades.The study may have important implications for public health and should be repeated with a larger sample, the researchers said.”These results, combined with present and future corroborating evidence, could inform clinical practice around helping adolescents reduce sugar-sweetened beverage intake, have important implications for messaging in public health campaigns, and inform the need for efforts to reduce sugar-sweetened-beverage advertising to youth and those drinks’ availability in and around schools,” the report concluded. Source:https://www.ucdavis.edu/news/sugar-sweetened-beverages-are-harmful-health-and-may-be-addictive-researchers-suggestlast_img read more

FDA approves perfusion device to help increase access to more donor lungs

first_imgReviewed by James Ives, M.Psych. (Editor)Apr 27 2019The U.S. Food and Drug Administration today approved a device, called Xvivo Perfusion System with Steen Solution Perfusate, that can temporarily ventilate, oxygenate, and pump (perfuse) preservation solution through lungs that were initially thought to be unacceptable for transplant. The device allows the transplant team to perform a more careful assessment of lung function to get a better sense of how the organs are working when they are perfused with a solution outside the body to better determine whether the lungs can then be viable for transplant.The Xvivo Perfusion System was originally granted marketing authorization in 2014 under a humanitarian device exemption (HDE), a regulatory pathway that limits the device’s use to a maximum of 8,000 patients per year. Today’s approval through the FDA’s more stringent premarket approval (PMA) pathway does not limit yearly patient use of the device, thereby allowing an increased number of lungs to be available for transplant and potentially increasing the number of patients who can benefit from this technology.Lung transplantation remains the only known life-saving treatment for end-stage lung disease, but many patients die while waiting for suitable lungs to become available for transplant. On average, only 15 percent of lungs obtained from deceased donors are suitable for transplantation. This is because the physiological function of a large number of donor lungs is questionable due to, for example, poor lung quality or possible injury, or there is inadequate time to find a suitable donor-recipient match. Approximately 2,530 lung transplants were performed last year, according to the U.S. Department of Health and Human Services.”Sadly, too many patients on transplant lists die waiting for suitable lungs. Providing patients with access to safe medical devices that have the potential to be lifesaving remains a top FDA priority, and we support the development of innovative technologies that can increase the donor organ pool for transplant patients in need of suitable lungs,” said Benjamin Fisher, Ph.D., director of the Division of Reproductive, Gastro-renal, Urological Devices at the FDA’s Center for Devices and Radiological Health.Related StoriesNew drug provides hope for patients with Duchenne muscular dystrophyRewiring of nerves gives movement to paralyzed arms and handsNew target identified for treatment of idiopathic pulmonary fibrosisThe Xvivo Perfusion System works by allowing marginal quality lungs that initially failed to meet standard transplant criteria to be ventilated, oxygenated and perfused at a standard normal body temperature for up to five hours. This provides an opportunity for surgeons to reassess transplant suitability, allowing them to transplant a certain percentage of lungs that were initially deemed to be unsuitable. The device consists of a perfusion cart with mechanical and electrical components that ventilate, oxygenate and perfuse the lungs with a lung preservation solution.The FDA evaluated data from a study involving 332 sets of donor lungs that were allocated into three groups: one group served as the control and were lungs initially deemed suitable for transplant that were provided to 116 recipients after standard preservation; one group were lungs initially deemed unsuitable for transplant and, after being perfused with the Xvivo Perfusion System, were implanted into 110 recipients; the third group were perfused with the Xvivo Perfusion System and were still deemed not suitable after the perfusion, and therefore were not implanted into patients. The one-year survival rate was 94 percent for the control group compared to 86.4 percent for the lung perfusion patients. The difference in rates was not deemed to be clinically significant.The most common adverse events associated with this device include acute rejection, bronchial complications, respiratory failure and infections.The FDA granted the premarket approval to Xvivo Perfusion Inc. Premarket approval is the most stringent type of device marketing application required by FDA and is based on a determination by the FDA that the PMA application contains sufficient valid scientific evidence to provide reasonable assurance that the device is safe and effective for its intended use(s). Source:https://www.fda.govlast_img read more

Study finds persistently high rate of longterm opioid prescribing for older cancer

first_imgRaji said that the findings also underscore the urgent need for a nationwide study of patterns and outcomes of opioid therapy and the effectiveness and safety of other pain treatment options in this rapidly growing population.Source:University of Texas Medical Branch at GalvestonJournal reference:Raji,M. et al. (2019). Long‐Term Opioid Therapy in Older Cancer Survivors: A Retrospective Cohort Study. The Journal of the American Geriatrics Society. doi.org/10.1111/jgs.15945 Our study of 63,815 cancer survivors aged 66 years and older from the Texas Cancer Registry-Medicare linked database who had been diagnosed with cancer at least five years ago and had completed all cancer treatments found a persistently high rate of long-term opioid prescribing. The rate of extended opioid therapy for cancer patients diagnosed in 2008 was 7.1 percent before their cancer diagnosis but rose to 9.8 percent within a year of cancer treatments and to 13.3 percent five years after diagnosis.”Mukaila Raji, senior author, UTMB professor and director, Division of Geriatrics Medicine Opioid-based pain medications are a key part of the pain management plan for patients undergoing cancer treatment. About 28 percent of cancer survivors report moderate to severe pain even after curative anti-cancer treatment. The most common form of chronic pain in these people is neuropathic pain, which can last for months to years or even last throughout a lifetime. However, there have been growing concerns regarding long-term opioid therapy in older cancer survivors, a population at a high risk of opioid toxicities.The researchers also found that cancer survivors diagnosed in 2004-2008 had higher rates of opioid prescribing than those diagnosed in 1995-1998 and 1999-2003. Taken together, the predictors of more extended opioid therapy were years since diagnosis, female gender, urban location, lung cancer diagnosis, disability as a reason for Medicare entitlement, Medicaid eligibility and a history of depression or drug abuse. Our findings have the potential to guide public policy and clinical practice for safer and more effective pain treatments in elderly cancer survivors.”Mukaila Raji Reviewed by Kate Anderton, B.Sc. (Editor)May 14 2019Using Medicare data, new findings from The University of Texas Medical Branch at Galveston show for the first time that the rates of long term opiate therapy – a 90-day or more supply of opioids per year – for older cancer survivors remain high for at least five years in cancer survivors.The study also showed that cancer survivors diagnosed after 2004 had higher rates of opioid prescribing compared with those diagnosed earlier than 2004. These finding were recently published in The Journal of the American Geriatrics Society.last_img read more

Prostate cancer diagnosis gets a boost from MRI

first_imgAccording to researchers, this new method of diagnosing prostate cancers provides a clearer image of the tumour and this can help doctors decide the exact location from which the biopsy could be taken to be sure about the cancer. The team says that some men are at low risk of the malignant cancers. In these men, earlier unnecessary biopsies were performed to assess if they have the cancer. This new technique can eliminate the need for unnecessary biopsies in these men. Biopsies come with the risk of pain, bleeding, infections and injury. Eliminating unnecessary biopsies would be thus, welcome news.For the breakthrough, the PRECISION trial also won the UK Research Paper of the Year at the 2019 BMJ awards held in May. Study leader Professor Caroline Moore from UCL Division of Surgery and Interventional Science said in a statement, “This is fantastic news and means all men at risk of prostate cancer will now have an MRI scan before any biopsy. By having access to high quality MRI at the outset, doctors will be able to safely reassure men at lowest risk, and identify men most likely to benefit from treatment.” She added, “UCL has led the evidence gathering for MRI in men at risk of prostate cancer and it is great to see the UK being the first country to make a formal recommendation that it should be used in all men prior to a biopsy. The challenge now is to ensure the availability of high quality MRI across the NHS.”UCL’s Dean of Medical Sciences, Professor Mark Emberton, oversaw both the ladmark trials. He said in a statement, “We have been using MRI for men at risk of prostate cancer at UCL and UCLH for a decade, and it is heartening to see our research has come to full fruition with this unequivocal guidance, meaning all men will now get access to this cost-effective and transformative technology. Our PROMIS and PRECISION studies have shown MRI scans will result in fewer unnecessary invasive biopsies for men, and fewer important cancers missed.” He explained, “MRI for all men prior to biopsy of the prostate is the most important development in the management of men with early prostate cancer that we have had in the last 100 years.”The researchers explain that use of this technique of Multiparametric MRI would be more cost effective compared to traditional prostate biopsy because it takes less time and is more effective in diagnosing clinically significant cancers. The trial proved that a 10 minute scan could help become powerful screening tool for prostate cancers. Prof Emberton said, “I think that could revolutionise the way that we diagnose disease and hopefully identify men who would be better treated than not treated.”Related StoriesSpecial blood test may predict relapse risk for breast cancer patientsUsing machine learning algorithm to accurately diagnose breast cancerTrends in colonoscopy rates not aligned with increase in early onset colorectal cancerThe researchers add that prostate cancer is a slow growing cancer and men with the mpMRI scan saying they have no cancer at the age of 55 or 60 years, could be rest assured that they would be cancer-free for many years and even for life. Emberton said, “If your prostate comes back looking very clean … you’re probably very unlikely to develop prostate cancer. It may be once we learn a bit more about it that you need to refresh it every 10 years or something like that.”At present raised levels of the protein PSA in the blood are linked with growing prostate cancer while around 75 percent of the men with high levels of PSA do not need treatment for cancers and 15 percent with true aggressive cancers may present with normal PSA levels. This makes PSA an unreliable marker of the cancer, explain the researchers. Emberton said, “You end up with a lot of men being diagnosed with cancer that isn’t destined to kill them. What’s beautiful about MRI is it overlooks the many, many cancers which don’t need to be diagnosed.”An upcoming trial REIMAGINE this August costing £6 million would be funded by the Medical Research Council and Cancer Research UK and would include 1,000 men aged 55 to 75 for scans through two London GP surgeries. Emberton said that till date most men shied away from screening because of the uncomfortable per rectal examination (probing at the prostate with a gloved finger via the anus) and a painful biopsy. This new method is a 10 minute scan costing about £150 and can help make screening easier he said.Expert speakKaren Stalbow, the head of policy, knowledge and impact at Prostate Cancer UK hailed this new trial saying in a statement, “If the results are positive, then MRI scanning could offer a non-invasive first stage of prostate cancer diagnosis in the future.”Professor Hashim Ahmed, chairman of urology at Imperial College London, said, “In the future we might be able to justify screening all healthy older men for prostate cancer just as we do for women with breast cancer. This would be so useful as the number of men dying from prostate cancer has barely changed in the last two decades despite advances in treatment.”Prof Ros Eeles, professor of prostate cancer genetics at the Institute of Cancer Research in London, on the other hand was not so convinced. He said, “The use of MRI of the prostate will be important in general management of prostate cancer assessment. However, currently it is not at all clear that MRI will be reliable to detect all cancers. In men at higher genetic risk, there are studies being undertaken at the Institute of Cancer Research to assess if men who have a genetic predisposition to aggressive prostate cancer have changes on their MRI when they get prostate cancer. At present, it is not at all certain that it will be reliable to rely on MRI alone for this assessment.”A spokesman for NHS England said, “NHS England is already rolling out some of the latest developments in MRI scanning for prostate cancer diagnosis and care as part of the NHS Long Term Plan’s ambitions to catch more cancers earlier and save lives. This new test is potentially an exciting development that the NHS will look at as more evidence becomes available.” Sources: Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study, The Lancet, DOI:https://doi.org/10.1016/S0140-6736(16)32401-1, https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)32401-1/fulltext MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis, N Engl J Med 2018; 378:1767-1777, DOI: 10.1056/NEJMoa1801993, https://www.nejm.org/doi/full/10.1056/NEJMoa1801993?query=featured_home By Dr. Ananya Mandal, MDJun 9 2019Traditionally prostate cancers have been diagnosed using biopsies of the tumour masses. New research from researchers at University College London (UCL) has shown that a more accurate diagnostic means for prostate cancers is MRI scans and targeted biopsies. Following this research, the UK’s medical guidelines – National Institute for Health and Care Excellence (NICE), have been updated to include this new and more effective way of diagnosing prostate cancers.There are 130 cases of prostate cancer being diagnosed every day in the UK. The disease killed 11,631 men in 2016 say reports. Early and more effective screening and diagnosis can help save lives say experts.The NICE guidelines include multiparametric MRI (mpMRI) as the first and most important means of diagnosing clinically localized prostate cancers in men. The UCL researchers conducted two clinical trials called PROMIS and PRECISION in collaboration with University College London Hospitals (UCLH). The new guidelines were released last month.center_img Image Credit: Engagestock / Shutterstocklast_img read more

Ahmedabad amusement ride collapse Six booked for culpable homicide

first_img Next Press Trust of India AhmedabadJuly 15, 2019UPDATED: July 15, 2019 19:44 IST There were around 30 people on the ride at Kankaria Adventure Park on Sunday when it collapsed after a pipe of the main shaft broke. (PTI)Ahmedabad Police have registered an FIR against six people, including managing director of a company operating an amusement park here, a day after two persons were killed and 27 injured when a ride collapsed there, an official said on Monday.There were around 30 people on the ride at Kankaria Adventure Park on Sunday when it collapsed after a pipe of the main shaft broke.Gujarat Chief Minister Vijay Rupani has also ordered strict action against those responsible for the accident and has asked the authorities concerned to conduct safety checks of such rides before allowing them to operate.As per the FIR, six people – Super Star Amusement Private Limited’s managing director Ghanshyam Patel, his son Bhavesh Patel, manager Rajesh Chowksi, ride operators Yash Patel and Kishan Mohanti and helper Manish Vaghela – have been booked for culpable homicide not amounting to murder, the official said.”An inquiry is going on and we will soon arrest those named in the FIR,” Maninagar police station’s inspector S M Patel said.Meanwhile, Vijay Rupani said he has ordered strict action against those responsible for the accident.”I have also asked the authorities to conduct safety checks and only then allow such rides to operate in the state,” Vijay Rupani said.Those who died in the accident were identified as Manali Rajwadi (24) and Mohammad Javed (22), a police official said.Officials from the Forensic Science Laboratory also visited the spot and were trying to ascertain the exact cause of the accident.ALSO READ | People record Kankaria Ahmedabad joyride accident. Scary viral videoALSO READ | Chimpanzee escapes from cell in China zoo, kicks zookeeper. Video goes viralALSO WATCH | Child killed in giant wheel crash in Andhra Pradesh, 6 injuredFor the latest World Cup news, live scores and fixtures for World Cup 2019, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted byShahrukh Tags :Follow adventure parkFollow Amusement park accidentFollow AhmedabadFollow FIRFollow Vijay Rupani Ahmedabad amusement ride collapse: Six booked for culpable homicideThere were around 30 people on the ride at Kankaria Adventure Park on Sunday when it collapsed after a pipe of the main shaft broke.advertisementlast_img read more

AP building up right ecosystem for startups Winny Patro

first_imgWinny Patro, CEO, AP Innovation Society Andhra Pradesh The Andhra Pradesh government is laying emphasis on promoting emerging technologies and stimulating innovation to build up the right ecosystem for young entrepreneurs, especially for setting up start-ups, according to AP Innovation Society CEO Winny Patro.He said here that “earnest efforts are being made to draw not only young entrepreneurs from the State and the country, but even from abroad, to launch operations here, Amaravati, Tirupati, Anantapur and other places.”He said hackathons were being held regularly and the State gGovernment had tied up with agencies in Hong Kong and Israel to enable youngsters to pitch their innovative ideas and come forward to start their ventures with solutions to problems faced by the people and various corporates.He said that in the Slush-2018, a prestigious start-up event being organised in Helsinki (Finland) on December 4 and 5, out of 30 start-ups 10 based in AP had been selected for participation by the Department of Industrial Policy and Promotion.Patra said the State government was encouraging out-of-the-box ideas from youngsters to convert them later into commercial ventures. “We are adopting various strategies to strengthen the start-up ecosystem by providing a network of venture capital funding firms, mentorship, incubation and acceleration. Selected global companies in various hackathons are also asked to start their operations in the State after offering them several incentives,” he added. Published on COMMENTS SHAREcenter_img start ups SHARE SHARE EMAIL COMMENT November 28, 2018last_img read more

Railways to recruit 13 lakh people 13000 hires to be made under

first_imgH.P. to implement 10% quota for general category soon: CM 10 per cent quota Bill challenged in Apex court January 23, 2019 10 PER CENT QUOTAThe 124th Amendment: A look at the facts Passage of quota Bill victory of social justice: Modi COMMENT RELATED SHARE SHARE EMAIL The Railways plans to be the first government department to hire people under the 10 per cent quota for the Economical Weaker Section (EWS). About 13,000 people will join the organisation in the first phase of hiring under the newly announced quota. The first phase of fresh recruitment for 1,31,328 posts shall be initiated in February-March 2019, said an official release. Around 10 per cent of these vacancies (around 13,100) shall be filled in from the EWS. This recruitment shall be completed by April-May 2020. First ministry“Railways will be the first ministry to start the hiring process with a 10 per cent quota for the economic weaker section,” Railway Minister Piyush Goyal said here on Wednesday. The first phase, to hire 1.32 lakh employees, will start after a tender for selection of the examination agency, he added.With approximately 53,000 and 46,000 employees retiring in 2019-20 and 2020-21 respectively, an additional 99,000 posts will be vacant. This will result in demand for almost 2.3 lakh vacancies, creating opportunities for 23,000 posts for the EWS in two phases.The recruitment for 1.51 lakh posts is on, leaving over 1.31 posts vacant. 10% EWS quota due to political will of my govt: Modi SHARE Amid quota battle, govts yet to fill 28 lakh jobs Published on Aims to be first ministry to hire under EWS quota UP govt nod to quota for poor among upper castes Reservation COMMENTSlast_img read more

Passenger nabbed from Kannur airport with Rs 7 lakh worth narcotics

first_img Asian News International KannurJuly 13, 2019UPDATED: July 13, 2019 16:42 IST The narcotics were detected concealed in the sole of the passenger’s slippers. (Photo: ANI)Central Industrial Security Force personnel on Friday apprehended from the Kannur International airport a Doha-bound passenger who was allegedly carrying hashish estimated to be worth Rs 7 lakh.The accused has been handed over to Narcotics Control Bureau for further legal action.Upon frisking, the passenger, identified as Ajas Valiyaballath was discovered to have hidden a 210 grams of hashish in his pelvic area.Upon intensive screening a total of 690 grams of hashish was detected concealed in the sole of the passenger’s slippers.A resident of Thayetheru, the passenger, Ajas Valiyaballath was travelling to Doha from Kannur. He was handed over by CISF to Narcotics Control Bureau along with the seized drugs.Also Read | Group of drug addicts in Punjab village contracts AIDS, Hepatitis after using same needleAlso Watch | High Way: How drugs addiction impacting youth in J&KFor the latest World Cup news, live scores and fixtures for World Cup 2019, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted byShifa Naseer Tags :Follow Narcotics Next Passenger nabbed from Kannur airport with Rs 7 lakh worth narcoticsUpon frisking, the passenger, identified as Ajas Valiyaballath was discovered to have hidden a 210 grams of hashish in his pelvic area.advertisementlast_img read more