Genetic marker predictor of early relapse in common childhood cancer discovered

Reviewed by James Ives, M.Psych. (Editor)Dec 14 2018Nova Southeastern University (NSU) researchers recently discovered that by testing the level of NER (nucleotide excision repair) gene expression, pediatric oncologists can determine the likelihood of early relapse (less than three years) in their acute lymphoblastic leukemia (ALL) patients. This is a critical finding because NER gene expression levels can now help guide doctors in their rationale for appropriate treatment targeted to each patient’s disease.Related StoriesGenetic contribution to distractibility helps explain procrastinationNew study identifies eight genetic variants associated with anorexia nervosaResearchers identify gene mutations linked to leukemia in children with Down’s syndromeALL is the most common childhood cancer. Treatment has improved dramatically due to evolving methods of determining risk factors and genetic analysis. Five-year survival rates have increased substantially from 57% in 1975 – ’77 to 92% in 2006 – ’12. Yet, the current genotoxic chemotherapy regimens are still extremely debilitating.”Our research found a correlation between high NER expression levels and early relapse of ALL among relapsing patients,” said Jean Latimer, Ph.D., director of the NSU AutoNation Institute for Breast and Solid Tumor Cancer Research and associate professor and cancer research scientist in NSU’s College of Pharmacy. “Being able to identify patients with the highest risk of early recurrence who are not detectable using present clinical measures and then treating them with a more targeted therapy is crucial to overcoming the cancer.”This is critical, according to the research recently published in the peer-reviewed journal, BMC Medical Genomics, because while ALL is much more treatable than in the past, the survival rate after relapse is poor.”By being able to accurately predict if a child’s cancer is likely to recur early or not, we may also spare many children who have low NER levels from the most toxic chemo regimens,'” said Latimer. Source: read more

Insilico Medicine to present latest advances in aging biomarker development at Longevity

first_img Source: Reviewed by James Ives, M.Psych. (Editor)Jan 25 2019Insilico Medicine, a Rockville-based company developing the end-to-end drug discovery pipeline utilizing the next generation artificial intelligence, will present its latest advances in human aging biomarker development at the Longevity Leaders Conference in London, 4 of February.Artificial Intelligence (AI) techniques, such as deep learning (DL) and reinforcement learning (RL) play a pivotal role in studying the biology of aging on many levels. The panel discussion will focus on the new frontiers in the biology of aging and the future of longevity science. Another major point of discussion is how technology and industry collaborations can drive successful outcomes in longevity science.Related StoriesTAU’s new Translational Medical Research Center acquires MILabs’ VECTor PET/SPECT/CTResearch sheds light on sun-induced DNA damage and repairScientists develop universal FACS-based approach to heterogenous cell sorting, propelling organoid research”We are happy to present our latest research at the Longevity Leaders Conference, which gathers the leading longevity scientists and investors. The topic of AI for Aging research and Productive longevity is rapidly gaining popularity, and we are happy to be at the leading edge of this research and one of the innovation drivers in the area”, says Alex Zhavoronkov, Ph.D., Founder, and CEO of Insilico Medicine, Inc.The Longevity Leaders Conference brings together key opinion leaders, CEOs, innovators and disruptors from the world of life sciences, technology, financial services, government and the investment community, to discuss how the grand challenges of Longevity can be tackled, how the significant opportunities can be seized, and to forge the partnerships and relationships to succeed in this new age. The Longevity Leaders Conference is held on February 4 in London.last_img read more

FDA approves perfusion device to help increase access to more donor lungs

first_imgReviewed by James Ives, M.Psych. (Editor)Apr 27 2019The U.S. Food and Drug Administration today approved a device, called Xvivo Perfusion System with Steen Solution Perfusate, that can temporarily ventilate, oxygenate, and pump (perfuse) preservation solution through lungs that were initially thought to be unacceptable for transplant. The device allows the transplant team to perform a more careful assessment of lung function to get a better sense of how the organs are working when they are perfused with a solution outside the body to better determine whether the lungs can then be viable for transplant.The Xvivo Perfusion System was originally granted marketing authorization in 2014 under a humanitarian device exemption (HDE), a regulatory pathway that limits the device’s use to a maximum of 8,000 patients per year. Today’s approval through the FDA’s more stringent premarket approval (PMA) pathway does not limit yearly patient use of the device, thereby allowing an increased number of lungs to be available for transplant and potentially increasing the number of patients who can benefit from this technology.Lung transplantation remains the only known life-saving treatment for end-stage lung disease, but many patients die while waiting for suitable lungs to become available for transplant. On average, only 15 percent of lungs obtained from deceased donors are suitable for transplantation. This is because the physiological function of a large number of donor lungs is questionable due to, for example, poor lung quality or possible injury, or there is inadequate time to find a suitable donor-recipient match. Approximately 2,530 lung transplants were performed last year, according to the U.S. Department of Health and Human Services.”Sadly, too many patients on transplant lists die waiting for suitable lungs. Providing patients with access to safe medical devices that have the potential to be lifesaving remains a top FDA priority, and we support the development of innovative technologies that can increase the donor organ pool for transplant patients in need of suitable lungs,” said Benjamin Fisher, Ph.D., director of the Division of Reproductive, Gastro-renal, Urological Devices at the FDA’s Center for Devices and Radiological Health.Related StoriesNew drug provides hope for patients with Duchenne muscular dystrophyRewiring of nerves gives movement to paralyzed arms and handsNew target identified for treatment of idiopathic pulmonary fibrosisThe Xvivo Perfusion System works by allowing marginal quality lungs that initially failed to meet standard transplant criteria to be ventilated, oxygenated and perfused at a standard normal body temperature for up to five hours. This provides an opportunity for surgeons to reassess transplant suitability, allowing them to transplant a certain percentage of lungs that were initially deemed to be unsuitable. The device consists of a perfusion cart with mechanical and electrical components that ventilate, oxygenate and perfuse the lungs with a lung preservation solution.The FDA evaluated data from a study involving 332 sets of donor lungs that were allocated into three groups: one group served as the control and were lungs initially deemed suitable for transplant that were provided to 116 recipients after standard preservation; one group were lungs initially deemed unsuitable for transplant and, after being perfused with the Xvivo Perfusion System, were implanted into 110 recipients; the third group were perfused with the Xvivo Perfusion System and were still deemed not suitable after the perfusion, and therefore were not implanted into patients. The one-year survival rate was 94 percent for the control group compared to 86.4 percent for the lung perfusion patients. The difference in rates was not deemed to be clinically significant.The most common adverse events associated with this device include acute rejection, bronchial complications, respiratory failure and infections.The FDA granted the premarket approval to Xvivo Perfusion Inc. Premarket approval is the most stringent type of device marketing application required by FDA and is based on a determination by the FDA that the PMA application contains sufficient valid scientific evidence to provide reasonable assurance that the device is safe and effective for its intended use(s). Source:https://www.fda.govlast_img read more

Study finds persistently high rate of longterm opioid prescribing for older cancer

first_imgRaji said that the findings also underscore the urgent need for a nationwide study of patterns and outcomes of opioid therapy and the effectiveness and safety of other pain treatment options in this rapidly growing population.Source:University of Texas Medical Branch at GalvestonJournal reference:Raji,M. et al. (2019). Long‐Term Opioid Therapy in Older Cancer Survivors: A Retrospective Cohort Study. The Journal of the American Geriatrics Society. Our study of 63,815 cancer survivors aged 66 years and older from the Texas Cancer Registry-Medicare linked database who had been diagnosed with cancer at least five years ago and had completed all cancer treatments found a persistently high rate of long-term opioid prescribing. The rate of extended opioid therapy for cancer patients diagnosed in 2008 was 7.1 percent before their cancer diagnosis but rose to 9.8 percent within a year of cancer treatments and to 13.3 percent five years after diagnosis.”Mukaila Raji, senior author, UTMB professor and director, Division of Geriatrics Medicine Opioid-based pain medications are a key part of the pain management plan for patients undergoing cancer treatment. About 28 percent of cancer survivors report moderate to severe pain even after curative anti-cancer treatment. The most common form of chronic pain in these people is neuropathic pain, which can last for months to years or even last throughout a lifetime. However, there have been growing concerns regarding long-term opioid therapy in older cancer survivors, a population at a high risk of opioid toxicities.The researchers also found that cancer survivors diagnosed in 2004-2008 had higher rates of opioid prescribing than those diagnosed in 1995-1998 and 1999-2003. Taken together, the predictors of more extended opioid therapy were years since diagnosis, female gender, urban location, lung cancer diagnosis, disability as a reason for Medicare entitlement, Medicaid eligibility and a history of depression or drug abuse. Our findings have the potential to guide public policy and clinical practice for safer and more effective pain treatments in elderly cancer survivors.”Mukaila Raji Reviewed by Kate Anderton, B.Sc. (Editor)May 14 2019Using Medicare data, new findings from The University of Texas Medical Branch at Galveston show for the first time that the rates of long term opiate therapy – a 90-day or more supply of opioids per year – for older cancer survivors remain high for at least five years in cancer survivors.The study also showed that cancer survivors diagnosed after 2004 had higher rates of opioid prescribing compared with those diagnosed earlier than 2004. These finding were recently published in The Journal of the American Geriatrics Society.last_img read more

Prostate cancer diagnosis gets a boost from MRI

first_imgAccording to researchers, this new method of diagnosing prostate cancers provides a clearer image of the tumour and this can help doctors decide the exact location from which the biopsy could be taken to be sure about the cancer. The team says that some men are at low risk of the malignant cancers. In these men, earlier unnecessary biopsies were performed to assess if they have the cancer. This new technique can eliminate the need for unnecessary biopsies in these men. Biopsies come with the risk of pain, bleeding, infections and injury. Eliminating unnecessary biopsies would be thus, welcome news.For the breakthrough, the PRECISION trial also won the UK Research Paper of the Year at the 2019 BMJ awards held in May. Study leader Professor Caroline Moore from UCL Division of Surgery and Interventional Science said in a statement, “This is fantastic news and means all men at risk of prostate cancer will now have an MRI scan before any biopsy. By having access to high quality MRI at the outset, doctors will be able to safely reassure men at lowest risk, and identify men most likely to benefit from treatment.” She added, “UCL has led the evidence gathering for MRI in men at risk of prostate cancer and it is great to see the UK being the first country to make a formal recommendation that it should be used in all men prior to a biopsy. The challenge now is to ensure the availability of high quality MRI across the NHS.”UCL’s Dean of Medical Sciences, Professor Mark Emberton, oversaw both the ladmark trials. He said in a statement, “We have been using MRI for men at risk of prostate cancer at UCL and UCLH for a decade, and it is heartening to see our research has come to full fruition with this unequivocal guidance, meaning all men will now get access to this cost-effective and transformative technology. Our PROMIS and PRECISION studies have shown MRI scans will result in fewer unnecessary invasive biopsies for men, and fewer important cancers missed.” He explained, “MRI for all men prior to biopsy of the prostate is the most important development in the management of men with early prostate cancer that we have had in the last 100 years.”The researchers explain that use of this technique of Multiparametric MRI would be more cost effective compared to traditional prostate biopsy because it takes less time and is more effective in diagnosing clinically significant cancers. The trial proved that a 10 minute scan could help become powerful screening tool for prostate cancers. Prof Emberton said, “I think that could revolutionise the way that we diagnose disease and hopefully identify men who would be better treated than not treated.”Related StoriesSpecial blood test may predict relapse risk for breast cancer patientsUsing machine learning algorithm to accurately diagnose breast cancerTrends in colonoscopy rates not aligned with increase in early onset colorectal cancerThe researchers add that prostate cancer is a slow growing cancer and men with the mpMRI scan saying they have no cancer at the age of 55 or 60 years, could be rest assured that they would be cancer-free for many years and even for life. Emberton said, “If your prostate comes back looking very clean … you’re probably very unlikely to develop prostate cancer. It may be once we learn a bit more about it that you need to refresh it every 10 years or something like that.”At present raised levels of the protein PSA in the blood are linked with growing prostate cancer while around 75 percent of the men with high levels of PSA do not need treatment for cancers and 15 percent with true aggressive cancers may present with normal PSA levels. This makes PSA an unreliable marker of the cancer, explain the researchers. Emberton said, “You end up with a lot of men being diagnosed with cancer that isn’t destined to kill them. What’s beautiful about MRI is it overlooks the many, many cancers which don’t need to be diagnosed.”An upcoming trial REIMAGINE this August costing £6 million would be funded by the Medical Research Council and Cancer Research UK and would include 1,000 men aged 55 to 75 for scans through two London GP surgeries. Emberton said that till date most men shied away from screening because of the uncomfortable per rectal examination (probing at the prostate with a gloved finger via the anus) and a painful biopsy. This new method is a 10 minute scan costing about £150 and can help make screening easier he said.Expert speakKaren Stalbow, the head of policy, knowledge and impact at Prostate Cancer UK hailed this new trial saying in a statement, “If the results are positive, then MRI scanning could offer a non-invasive first stage of prostate cancer diagnosis in the future.”Professor Hashim Ahmed, chairman of urology at Imperial College London, said, “In the future we might be able to justify screening all healthy older men for prostate cancer just as we do for women with breast cancer. This would be so useful as the number of men dying from prostate cancer has barely changed in the last two decades despite advances in treatment.”Prof Ros Eeles, professor of prostate cancer genetics at the Institute of Cancer Research in London, on the other hand was not so convinced. He said, “The use of MRI of the prostate will be important in general management of prostate cancer assessment. However, currently it is not at all clear that MRI will be reliable to detect all cancers. In men at higher genetic risk, there are studies being undertaken at the Institute of Cancer Research to assess if men who have a genetic predisposition to aggressive prostate cancer have changes on their MRI when they get prostate cancer. At present, it is not at all certain that it will be reliable to rely on MRI alone for this assessment.”A spokesman for NHS England said, “NHS England is already rolling out some of the latest developments in MRI scanning for prostate cancer diagnosis and care as part of the NHS Long Term Plan’s ambitions to catch more cancers earlier and save lives. This new test is potentially an exciting development that the NHS will look at as more evidence becomes available.” Sources: Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study, The Lancet, DOI:, MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis, N Engl J Med 2018; 378:1767-1777, DOI: 10.1056/NEJMoa1801993, By Dr. Ananya Mandal, MDJun 9 2019Traditionally prostate cancers have been diagnosed using biopsies of the tumour masses. New research from researchers at University College London (UCL) has shown that a more accurate diagnostic means for prostate cancers is MRI scans and targeted biopsies. Following this research, the UK’s medical guidelines – National Institute for Health and Care Excellence (NICE), have been updated to include this new and more effective way of diagnosing prostate cancers.There are 130 cases of prostate cancer being diagnosed every day in the UK. The disease killed 11,631 men in 2016 say reports. Early and more effective screening and diagnosis can help save lives say experts.The NICE guidelines include multiparametric MRI (mpMRI) as the first and most important means of diagnosing clinically localized prostate cancers in men. The UCL researchers conducted two clinical trials called PROMIS and PRECISION in collaboration with University College London Hospitals (UCLH). The new guidelines were released last month.center_img Image Credit: Engagestock / Shutterstocklast_img read more

Machine tools receiving a checkup

The researchers configure the measuring nest. Credit: Fraunhofer IWU Explore further Machine tools are thermally sensitive: operational precision can be disrupted when hall doors are opened in the winter, even for a brief period of time. Most companies have manufacturing facilities situated around the world, often in environments without air conditioning. The result is machinery imprecision and product rejections. Power units and other heat sources like hot tools can also have a negative effect. In a recently inaugurated climate chamber that is one of a kind worldwide, researchers at Fraunhofer IWU in Chemnitz are studying the influence that climate conditions and ambient interactions exert on machine tools and their components. “Exposure to sunlight and drafts causes thermal interactions in the form of structural stretching, which we are able to reproduce in the environmental chamber. The aim is to stabilize and enhance machine precision directly via a machine control system by correcting thermally-induced errors during operation,” explains Dr. Janine Glänzel, research scientist at Fraunhofer IWU. To cite an example, thermal influences particularly affect machines with long beds or vertically structured systems because they accumulate heat asymmetrically during operation and bend to one side.The research scientist and her team simulate a wide variety of temperature scenarios: In the newly inaugurated test lab, temperatures of 10 to 40 degrees Celsius can be configured with a tolerance of plus/minus 0.1 Kelvin as well as air humidity of 10 to 90 percent with a tolerance of three percent. “We turned the thermal chamber we had into an climate chamber. The new ventilation components, steam humidifier, and absorption dryer now enable us to control air humidity in addition to temperature,” says Glänzel. For example, the researcher and her colleagues are able to study the influence humidity has on the swelling properties of modern materials like wet mix concrete. Thanks to the removable ceiling, entire machine tools can be lifted into the climate chamber via crane. Credit: Fraunhofer IWU Thanks to a surface area of 40 square meters, a vertical clearance of 4.5 meters, and a removable ceiling, the environmental chamber is large enough to fit not only individual components, but also entire machine tools which are lifted into place by the hall crane. The temperature-controlled flooring is designed to hold a maximum weight of 20 tons. Provided by Fraunhofer-Gesellschaft Influences like temperature variation, drafts, and air humidity can heavily compromise precision. The Fraunhofer Institute for Machine Tools and Forming Technology IWU is exposing machines to various climate zones around the world without actually shipping them to Southeast Asia, Canada, or Brazil: A newly inaugurated climate chamber is able to test how ambient conditions affect the function of lathes and other machines. Citation: Machine tools receiving a check-up (2018, February 1) retrieved 18 July 2019 from Adapters enable better communication between machines Before initiating measurement, the researchers perform a simulation-based analysis to determine where best to place temperature and displacement sensors. The scientists adhere the temperature sensors directly to the machine, while the displacement sensors are mounted onto a measuring frame set up around the machine tool and linked via small rods to measuring blocks at neuralgic points—i.e. in locations where the researchers are able to measure the most influential thermal displacements. The temperature sensors enable them to measure the influence that internal and external thermal loads have on the machine structure. Temperature fluctuations are mapped automatically over the course of the experiment. It’s also possible to gauge the behavior of machine tools under long-term exposure. “The principle behind our sophisticated technology for cooling and heating functions like the climate control system in a car,” according to Glänzel. That means manufacturers and users alike have the ability to configure their machine tools in advance, and to adapt them to future ambient conditions.When displacement does arise, the researchers implement corrective algorithms they have developed themselves to adapt production precision. The measured values are integrated into the corrective process. “We calculate correction values directly via a reference point on the tool, known as the tool center point, so that thermal deformations during production can be corrected,” explains the mathematician with an affinity for technology. Additionally, the researchers determine the level of heat dissipation from the machine tools before transferring it to the cooling system to save energy.The climate chamber is the focal point of research in the special project Transregio 96, “Thermo-energetic design of machine tools,” which aims to adjust the parameters of energy use, precision, and productivity to achieve an optimal solution. The German Research Foundation (DFG, Deutsche Forschungsgemeinschaft) is sponsoring the research project. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. read more

SK Hynix posts record profits on rising demand

first_img SK Hynix posts record quarterly profits South Korea’s SK Hynix, the world’s second-largest memory chipmaker, posted record profits in the third quarter, the company said Thursday, citing resilient global demand. Explore further Net profit leaped 54 percent year-on-year to 4.7 trillion won (US$4.1 billion) in the July to September period, while operating profit also jumped 73 percent to 6.5 trillion won during the same period.The shipment of DRAM chips—commonly used in smartphones and computer servers—rose five percent from the previous quarter as “server demand stayed strong”, the chipmaker said in a statement.Sales of NAND Flash products saw a 19 percent quarterly leap “as the company actively responded to the market trend towards high-density mobile products”, it added.The South Korean company supplies chips to companies from US smartphone giant Apple to China’s Huawei Technologies and is investing billions of dollars to build more factories to meet rising demand.”SK Hynix plans to actively respond to market changes through the development of new processes as well as stable operation of mass production facilities,” it said.The company said an ongoing expansion of its Chinese lines and the completion of a new factory in Cheongju in South Korea this month “will contribute to the company’s production capacity from the first half of next year”.SK Hynix shares were down as much as 3.15 percent in early trading in Seoul. © 2018 AFP Citation: SK Hynix posts record profits on rising demand (2018, October 25) retrieved 17 July 2019 from This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.last_img read more

Using solar to light up communities grow incomes of rural households

first_imgImmaculate Tumwebaze, is a resident of Katara village, Kichwamba sub county, Rubirizi district. She is one of the 18 members of Katara Women Poverty Eradication Group (KWPEG) that have benefited from the Scaling-up rural electrification using innovative solar PV distribution models project by World Wide Fund for Nature Uganda Country Office (WWF-UCO) with funding from European Union. This project aims at increasing access to clean energy for lighting and cooking for households in the Albertine Graben. Provided by WWF Explore further Kenyan’s mission: solar lamps to empower the poor This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.center_img Credit: Happy Ali Citation: Using solar to light up communities, grow incomes of rural households (2018, November 28) retrieved 17 July 2019 from The mother of six says she does not regret the decision she took to get a loan from the saving scheme and pay for the solar since it has served her needs.Early November 2017, Tumwebaze acquired the solar from KIIMA FOODS, a project coordinating hub for the southern Albertine Graben with about eight districts.With the provision of paying in installments, she started with Shs 100,000 which is the 20 per cent of the total cost of the solar product.Tumwebaze has been paying about Shs 50,000 monthly, and is hopeful that she will finish her payments by the end of November 2018.”I had for the last nine years used the Kerosene lamps to provide light both at home and at the shop…this took a lot of money and even the light was not bright,” Tumwebaze narrates.She used to buy paraffin from Nyakasharu or Ndekye trading Centres which are about 10 kilometers away from her shop, adding that she would use paraffin of Shs 1,000 a day and transport of Shs 4,000 weekly.She adds that the kerosene lamps had put her health at risk since she would inhale intoxicated fumes from the lamp and the same fumes would also dirten everything in her house.”I also used to fear that at one time the kerosene lamp would cause fire that would burn my shop as it has ever happened to other people here,” she adds.But on top of all the other challenges of using a kerosene lamp, Tumwebaze also notes that the it would never provide a bright flame, something that thieves would see as a chance to steal items from her shop.”You know some of these customers are thieves. They would point at some product and when I turn to pick it, I find they have already stolen some other thing. This is no longer there. I have enough light,” Tumwebaze says.Additionally, Tumwebaze notes that with solar electricity now, she is able to charge her phone and cut on the expenses she used to incur when charging from other people’s homes that were also distant.Tumwebaze is hopeful that her son Monday Joseph who sat for his Primary Leaving Exams (UPE) this year will pass with flying colors since he utilized the light for his evening and morning revisions.last_img read more

European heavyweights Airbus Altran targeted by cyberattacks

first_imgAirbus says no commercial operations were impacted An Airbus spokesman said Thursday that the attack was detected on January 6 and that personal data on some European personnel was targeted starting January 10, prompting it to inform France’s data regulator CNIL the following day.Under the EU’s strict new General Data Protection Regulation (GDPR) enacted last year, companies must inform regulators within 72 hours if such attacks put personal data at risk. The Airbus inquiry is still underway to determine who was behind the attack, which focussed on the IT systems of its commercial aircraft division, the spokesman said.The group said no commercial operations were impacted by the breach, and that attackers appeared to be seeking contact and IT identification details of some of its 130,000 employees.The inquiry also aims to determine if specific data was being targeted at a key player in Europe’s defence and security industries.Airbus is a major supplier of military jets and weapons as well as communication and navigation satellites to European nations, generating revenue of 59 billion euros ($68 billion) in 2017.It also provides cybersecurity services for essential government networks and infrastructure. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Security experts said Altran was targeted by a ransomware attack © 2019 AFP Explore furthercenter_img Airbus sells 65 jets to SMBC Aviation Capital Infection risksAltran Technologies, one of the largest IT consulting firms in Europe, announced Monday that it had detected on January 24th an attack that impacted its operations on the continent.But unlike the Airbus attack, the hackers did not appear to be seeking personal data but rather access to files in “many European countries, including France.”Although Altran said it had not detected any cases of stolen data, it had to shut down its IT networks “to protect our clients, employees and partners.”Security experts said Altran was targeted by a ransomware attack, which usually attempts to lock a person or company out of key data, or threaten to publish the private data, unless a payment is made.And because modern companies share network services across several sites, “the files on central servers can be infected quite quickly,” said Ivan Fontarensky, head of cyberdefence at the French defence and electronics group Thales.Altran has brought in outside experts to help determine the origin and extent of the attack, and said that so far it “has not identified any stolen data, nor instances of a propagation of the incident to our clients.”The company’s clients operate in a wide range of sectors including defence, energy and infrastructure industries—and like Airbus, it also offers cybersecurity services.The EU moved to require companies to inform regulators of personal data breaches after accusing several high-profile companies of failing to inform users that passwords or personal data had been compromised by hackers.Experts say such disclosures are bound to increase in coming years as the digital economy takes hold in more countries and sectors. Citation: European heavyweights Airbus, Altran targeted by cyberattacks (2019, January 31) retrieved 17 July 2019 from European aerospace and defence group Airbus has launched an inquiry into the origin and targets of a cyberattack detected earlier in January, the same month that French IT consulting group Altran also saw attempts to breach its systems.last_img read more

Lyft revs up for an IPO seeking to raise 24bn

first_img Citation: Lyft revs up for an IPO seeking to raise $2.4bn (2019, March 18) retrieved 17 July 2019 from The San Francisco startup could be valued at more than $20 billion under the terms of the initial public offering unveiled Monday, setting a price per share of between $62 and $68.Lyft’s launch is the first of what is expected to be a wave of IPOs from venture-backed startups worth more than $1 billion, known in Silicon Valley as “unicorns.”Lyft’s listing comes ahead of a larger offering expected from Uber, which has a valuation of some $70 billion.Others expected to move to Wall Street this year include the business collaboration firm Slack, visual discovery startup Pinterest and possibly the big data group Palantir.Lyft is proposing to sell 30.8 million shares with an underwriters option for an additional 4.6 million, with shares on the Nasdaq listed under the symbol “LYFT.”No date was given for the listing, but the Wall Street Journal said Lyft shares could begin trading by the end of next week, when a final price will be set.’Sharing economy’ grows upLyft and Uber are among the most prominent players in the “sharing economy,” representing a trend that moves away from ownership to on-demand services. © 2019 AFP This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Lyft said Monday it would seek to raise as much as $2.4 billion in its public share offering, in the first major listing in the fast-growing ride-hailing sector. Members and supporters of the Independent Drivers Guild protest against Lyft, which is challenging the way the Taxi and Limousine Commission calculates the minimum wage for drivers Lyft is also betting on adoption of autonomous driving, claiming that self-driving taxis and rideshare services will help reshape urban landscapes by eliminating the need for private vehicles.”We believe that cities should be built for people, not cars,” Lyft says in its IPO filing. Explore further Lyft could be valued at more than $20 billion under the terms of the initial public offering “Mass car ownership strains our cities and reduces the very freedom that cars once provided.”Both Lyft and Uber have faced criticism for disrupting traditional taxi services and for using the model of drivers as independent contractors.The rideshare firms claim that most drivers prefer the flexible work arrangement, even if it offers fewer benefits and less job security.Lyft said it will seek to maintain its policy that drivers are independent contractors while noting that any legal challenge to this could have “adverse” consequences.For the IPO, Lyft said some shares would be reserved for drivers who have completed at least 10,000 trips using the platform.The company will offer a bonus of $1,000 to $10,000 to eligible drivers by March 19 that may be used to buy shares at the offering price, although they may opt to pocket the cash.Value trap?With a dual-class share structure enabling founders to maintain control, chief executive Logan Green will have some 29 percent of voting power and co-founder John Zimmer 19 percent after the IPO. Lyft has posted heavy losses but sees a future where people move away from private vehicles Spending for “on demand” services rose 58 percent in 2017 to $75.7 billion in the US The growth in these services is eroding sentiment for ownership of homes, cars and other goods, and is also shifting the concept of labor and employment, sparking fierce debates on whether the change is good or bad.Spending for “on demand” on services such as Uber and Airbnb and other digital platforms rose 58 percent in 2017 to $75.7 billion in the US, with more than 41 million consumers participating, according to a survey by Rockbridge Associates.Heavy lossesAccording to documents filed earlier, Lyft lost $911 million on $2.2 billion in 2018 revenues. The documents show revenues grew sharply from $343 million in 2016, but losses widened as well.Lyft said in its Securities and Exchange Commission filing it has completed over one billion rides since its inception in 2012 and had bookings last year of $8.1 billion. It has a 39 percent share of the US rideshare market, according to a survey cited in the filing. Lyft has also begun to move into other kinds of short-range transportation including bike- and scooter-sharing. Lyft set for March market debut: report Ross Gerber of the investment firm Gerber Kawasaki cautioned against getting too excited on Lyft.”Another very overpriced IPO which gives public shareholders no say,” Gerber said in a tweet. “Do not touch this dog. It will rally and then start the long road down.”Aswath Damodaran, a New York University business professor specializing in corporate valuations, said he calculates Lyft is worth around $16 billion.”I remain troubled by the ride sharing business model and its lack of clear pathways to profitability, but I think Lyft has picked the right strategy of staying focused both geographically (in the US) and in the transportation services business,” Damodaran said in a blog post earlier this month.The researcher said ride-hailing firms have produced changes in consumer behavior, suggesting growth ahead.”One of the striking features of the ride sharing revolution is how much it has changed consumer behavior, drawing people who would normally never have used car service into its reach,” he said.”I will assume that ride sharing will continue to draw new customers, from mass transit users to self-drivers, causing the transportations services market to double over the next 10 years.”last_img read more

Ahmedabad amusement ride collapse Six booked for culpable homicide

first_img Next Press Trust of India AhmedabadJuly 15, 2019UPDATED: July 15, 2019 19:44 IST There were around 30 people on the ride at Kankaria Adventure Park on Sunday when it collapsed after a pipe of the main shaft broke. (PTI)Ahmedabad Police have registered an FIR against six people, including managing director of a company operating an amusement park here, a day after two persons were killed and 27 injured when a ride collapsed there, an official said on Monday.There were around 30 people on the ride at Kankaria Adventure Park on Sunday when it collapsed after a pipe of the main shaft broke.Gujarat Chief Minister Vijay Rupani has also ordered strict action against those responsible for the accident and has asked the authorities concerned to conduct safety checks of such rides before allowing them to operate.As per the FIR, six people – Super Star Amusement Private Limited’s managing director Ghanshyam Patel, his son Bhavesh Patel, manager Rajesh Chowksi, ride operators Yash Patel and Kishan Mohanti and helper Manish Vaghela – have been booked for culpable homicide not amounting to murder, the official said.”An inquiry is going on and we will soon arrest those named in the FIR,” Maninagar police station’s inspector S M Patel said.Meanwhile, Vijay Rupani said he has ordered strict action against those responsible for the accident.”I have also asked the authorities to conduct safety checks and only then allow such rides to operate in the state,” Vijay Rupani said.Those who died in the accident were identified as Manali Rajwadi (24) and Mohammad Javed (22), a police official said.Officials from the Forensic Science Laboratory also visited the spot and were trying to ascertain the exact cause of the accident.ALSO READ | People record Kankaria Ahmedabad joyride accident. Scary viral videoALSO READ | Chimpanzee escapes from cell in China zoo, kicks zookeeper. Video goes viralALSO WATCH | Child killed in giant wheel crash in Andhra Pradesh, 6 injuredFor the latest World Cup news, live scores and fixtures for World Cup 2019, log on to Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted byShahrukh Tags :Follow adventure parkFollow Amusement park accidentFollow AhmedabadFollow FIRFollow Vijay Rupani Ahmedabad amusement ride collapse: Six booked for culpable homicideThere were around 30 people on the ride at Kankaria Adventure Park on Sunday when it collapsed after a pipe of the main shaft broke.advertisementlast_img read more

Flushed Goldfish Grew to Be KittenSize in Niagara River

first_img Image Gallery: Invasive Species A monstrously huge goldfish was recently captured in the Niagara River in New York. The goldfish was presumably a discarded house pet that may have been illegally released or survived a traumatic flush down a toilet. Buffalo Niagara Waterkeeper (BNW), a nonprofit working to protect and restore the Niagara River and Lake Erie watershed, caught and photographed the giant goldfish in the river’s Black Rock Canal, sharing an image in a Facebook post on June 14. [In Photos: Thousands of Goldfish Swarm in Colorado Lake] In the photo, Marcus Rosten, an employee of the nonprofit, cradles the fish in two hands; the orange leviathan measured a whopping 14 inches (36 centimeters) long, according to the post.These Sharks Were Too Busy to Notice a Bigger Predator Watching ThemThe unexpected twist at the end of this feeding frenzy delighted scientists.Credit: NOAA Office of Ocean Exploration and Research, Windows to the Deep 2019Your Recommended PlaylistVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9接下来播放Headbutting Tiny Worms Are Really, Really Loud00:35关闭选项Automated Captions – en-US facebook twitter 发邮件 reddit 链接已复制直播00:0002:2802:28 An even more supersized goldfish was nabbed in California’s Lake Tahoe in 2013; it weighed in at just over 4 lbs. (2 kilograms) and measured nearly 2 feet (61 cm) long. Goldfish (Carassius auratus auratus) are native to eastern Asia and belong to the carp family. They usually reach about 1 to 2 inches (3 to 5 cm) in length when they live in aquariums or small fish tanks; at most, they grow to about 6 inches (15 cm) in captivity, according to the New York State Department of Environmental Conservation (DEC). But when goldfish are released into streams and rivers, they often grow to be 12 to 14 inches (31 to 36 cm) long. The first sightings of goldfish in New York waterways date to 1842; more than a dozen other states also noted the appearance of goldfish in rivers and streams by the end of the 19th century, according to the U.S. Geological Survey. Today, goldfish can be found in waterways across New York State, “the result of illegally released pets or escapees from bait buckets,” the DEC reported. The fish can survive year-round in the Lake Erie watershed, and goldfish reproduce very quickly; a handful of goldfish released into a Colorado lake in 2012 multiplied to number in the thousands just three years later. Invasive goldfish directly compete with native fish, and in large numbers, they upset the natural biodiversity of vulnerable freshwater environments, a BNW representative told Live Science in an email. “Aquatic invasive species that don’t naturally belong in the Great Lakes, like this goldfish, are a constant threat to the health of native wildlife populations and their habitats,” the representative said. Across all of the Great Lakes, goldfish populations are estimated to run into the tens of millions, the BNW posted on Facebook. Photos: Giant Goldfish & Other Freaky Fish Alien Invaders: Destructive Invasive Species Originally published on Live Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksYou May LikeVikings: Free Online GamePlay this for 1 minute and see why everyone is addictedVikings: Free Online GameUndoMarie Claire | HanacureMeet The Beauty Equivalent To TIME’s Person Of The Year AwardMarie Claire | HanacureUndoPrimeSolarQuotesCalifornia Signs Solar Law Helping Homeowners Save Hundreds A Month.PrimeSolarQuotesUndoClassmatesSearch For Any High School Yearbook, It’s Free.ClassmatesUndoDr. Marty Nature's Feast Freeze-Dried RAW Cat Food3 Signs Something’s Wrong Inside Your Cat’s BodyDr. Marty Nature’s Feast Freeze-Dried RAW Cat FoodUndoAncestryThe Story Behind Your Last Name Will Surprise YouAncestryUndolast_img read more

Space Archaeology Is a Thing And It Involves Lasers and Spy Satellites

first_img An eye inlay from a tomb dating to 4,000 years ago, in Lisht, Egypt. The expedition, co-led by Dr. Parcak, was conducted in partnership with the Egyptian Ministry of Antiquities. Credit: Courtesy of Sarah Parcak In Photos: Ancient Egyptian Tombs Decorated with Creatures Today, aerial or satellite images captured by optical lenses, thermal cameras, infrared and lidar — light detection and ranging, a type of laser system — are well-established as part of an archaeologist’s tool kit. And archaeologists need as many tools as they can get; there are thought to be millions of sites around the world that are yet to be discovered, Parcak added. But remote sensing isn’t one-size-fits-all; different terrains require different space archaeology techniques. For example, in Egypt, layers of sand blanket lost pyramids and cities. In that type of landscape, high-resolution optical satellites reveal subtle differences on the surface that may hint at structures underground. And in regions with dense vegetation, such as in Southeast Asia or Central America, lidar emits millions of pulses of light to penetrate beneath the trees and detect hidden buildings, Parcak explained. In her own work, Parcak’s analysis of satellite views led to the creation of a new map for the legendary city of Tanis in Egypt, famously featured in the movie “Raiders of the Lost Ark.” Satellite images of Tanis revealed a vast network of the city’s buildings, which had previously gone undetected even as the site was under excavation, she wrote. Image Gallery: How Technology Reveals Hidden Art Treasures What does it take to be a space archaeologist? No, you don’t need a rocket or a spacesuit. However, lasers are sometimes involved. And infrared cameras. And spy satellites. Welcome to Sarah Parcak’s world. Parcak, an archaeologist and a professor of anthropology at the University of Alabama at Birmingham, has mapped sites around the world from space; she does so using images captured by satellites — from NASA and from private companies — orbiting high above the ground. From these lofty heights, sensitive instruments can reveal details that are invisible to scientists on the ground, marking the positions of walls or even entire cities that have been buried for millennia. Parcak unpacks how views from space are transforming the field of archaeology, in her new book “Archaeology From Space: How the Future Shapes Our Past” (Henry Holt and Co., 2019). [Read an excerpt from “Archaeology From Space”] AdvertisementArchaeology Gets a Sci-Fi Makeover, In ‘Archaeology From Space’Live Science sits down with archaeologist and author Sarah Parcak to talk about her new book, “”Archaeology From Space: How the Future Shapes Our Past” (Henry Holt and Co., 2019).Volume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9接下来播放Fomalhaut Stars Huge Ring of Dusty Debris Captured by ALMA | Video00:54关闭选项Automated Captions – en-US facebook twitter 发邮件 reddit 链接已复制直播00:0020:0420:04Your Recommended Playlist00:54Fomalhaut Stars Huge Ring of Dusty Debris Captured by ALMA | Video00:43OTD in Space – July 16: Apollo 11 Launches to the Moon13:13Apollo 11 Astronaut Michael Collins Talks Launch on 50th Anniversary06:26How To Find Jupiter and Other Skywatching Objects in July 2016 | Builds: Lego NASA Apollo Saturn V Rocket02:22Skywatching Planets and the Harvest Moon In September 2014 | Video关闭 Satellites analyze landscapes and use different parts of the light spectrum to uncover buried remnants of ancient civilizations. But studying archaeological sites from above had very humble (and low-tech) beginnings, Parcak told Live Science. Researchers first experimented with peering down from a great height at a historic location more than a century ago, when a member of the Corps of Royal Engineers photographed the 5,000-year-old monument Stonehenge from a hot-air balloon. “You could even see — from this very early and somewhat blurry photograph — staining in the landscape around the site, showing that there were buried features there,” Parcak said. Through the 1960s and into the 1970s, aerial photography continued to play an important role in archaeology. But when NASA launched its first satellites it opened up “a completely new world,” for archaeologists in the 1980s and 1990s, Parcak said. In fact, declassified images from the U.S. government’s Corona spy satellite program, which operated from 1959 to 1972, helped archaeologists in the 1990s to reconstruct the positions of important sites in the Middle East that had since disappeared, eradicated by urban expansion.center_img 7 Amazing Places to Visit with Google Street View Satellite images of the buried ancient Egyptian city Tanis revealed city walls that were invisible to archaeologists on the ground. Credit: Courtesy of Sarah Parcak Originally published on Live Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksYou May LikeVikings: Free Online GamePlay this for 1 min and see why everyone is addicted!Vikings: Free Online GameUndoTruthFinder People Search SubscriptionOne Thing All Liars Have in Common, Brace YourselfTruthFinder People Search SubscriptionUndoSoGoodlyThey Were Named The Most Beautiful Twins In The World, Wait Till You See Them TodaySoGoodlyUndoBeverly Hills MDPlastic Surgeon Reveals: “You Can Fill In Wrinkles At Home” (Here’s How)Beverly Hills MDUndoGundry MD Total Restore SupplementU.S. Cardiologist: It’s Like a Pressure Wash for Your InsidesGundry MD Total Restore SupplementUndoBirch Gold GroupThis IRS Tax Law is Sweeping the U.S.Birch Gold GroupUndo If these stories of space archaeology in Parcak’s book leave readers wanting more, they’re in luck. An online platform called GlobalXplorer, launched and run by Parcak, offers users access to a library of satellite images for browsing and annotation. Aspiring “citizen-scientists” can join “campaigns” to assist in the ongoing search for lost cities and ancient structures, and to help experts identify signs of looting in vulnerable sites, according to the platform website. Since 2017, approximately 80,000 users have evaluated 14 million satellite images, mapping 700 major archaeological sites that were previously unknown, Parcak said. “Archaeology From Space” is available to buy on Amazon.last_img read more

Dont Waste Your Emotions on Plants They Have No Feelings Grumpy Scientists

first_imgA tree falls in the woods; but whether or not anyone hears it, the tree has no regrets. Nor does it experience fear, anger, relief or sadness as it topples to the ground. Trees — and all plants, for that matter — feel nothing at all, because consciousness, emotions and cognition are hallmarks of animals alone, scientists recently reported in an opinion article. The idea that plants have some degree of consciousness first took root in the early 2000s; the term “plant neurobiology” was coined around the notion that some aspects of plant behavior could be compared to intelligence in animals. Though plants lack brains, the firing of electrical signals in their stems and leaves nonetheless triggered responses that hinted at consciousness, researchers previously reported. But such an idea is bunk, according to the authors of the new article. Plant biology is complex and fascinating, but it differs so greatly from that of animals that so-called evidence of plants’ intelligence is intriguing but inconclusive, the scientists wrote. [The 5 Smartest Non-Primates on the Planet] Plants Know Their SiblingsPlants use chemical cues to recognize and cooperate with siblings, while spurring competition among rivals.Volume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9接下来播放Better Bug Sprays?01:33关闭选项Automated Captions – en-US facebook twitter 发邮件 reddit 链接已复制直播00:0001:2701:27Your Recommended Playlist01:33Better Bug Sprays?04:24Sperm Whale Befriends Underwater Robot01:08Why Do French Fries Taste So Bad When They’re Cold?00:29Robot Jumps Like a Grasshopper, Rolls Like a Ball00:29Video – Giggly Robot02:31Surgical Robotics关闭 Originally published on Live Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksYou May LikeVikings: Free Online GamePlay this for 1 min and see why everyone is addicted!Vikings: Free Online GameUndoTruthFinder People Search SubscriptionOne Thing All Liars Have in Common, Brace YourselfTruthFinder People Search SubscriptionUndoGundry MD Total Restore SupplementU.S. Cardiologist: It’s Like a Pressure Wash for Your InsidesGundry MD Total Restore SupplementUndoTop 10 Best Meal DeliveryMeal Kit Wars: 10 Tested & Ranked. See Who WonTop 10 Best Meal DeliveryUndoNucificTop Dr. Reveals The 1 Nutrient Your Gut Must HaveNucificUndoComparisons.org2019: Little-Known Rule in Rowland Heights, Image Gallery: Carnivorous Plants in Action In Photos: Plants in Danger of Disappearingcenter_img In animals, neurobiology refers to the biological mechanisms through which a nervous system regulates behavior, according to Harvard University’s Mind Brain Behavior Interfaculty Initiative. Over millions of years, brains in diverse animal species have evolved to produce behaviors that experts identify as intelligent: Among them are reasoning and problem-solving, tool use and self-recognition. Beginning in 2006, some scientists have argued that plants possess neuron-like cells that interact with hormones and neurotransmitters, forming “a plant nervous system, analogous to that in animals,” said lead study author Lincoln Taiz, a professor emeritus of molecular, cell and developmental biology at the University of California Santa Cruz. “They even claimed that plants have ‘brain-like command centers’ at their root tips,” Taiz told Live Science in an email. This perspective makes sense if you simplify the workings of a complex brain, reducing it to an array of electrical pulses; cells in plants also communicate through electrical signals, according to the article. However, the signaling in a plant is only superficially similar to the billions of synapses firing in a complex animal brain, which is more than “a mass of cells that communicate by electricity,” Taiz said. “For consciousness to evolve, a brain with a threshold level of complexity and capacity is required,” he added. Other researchers who recently investigated the neuroscience of consciousness — awareness of one’s world and a sense of self — found that in animals, only vertebrates, arthropods and cephalopods had brains complex enough to enable them to be conscious. “If the lower animals — which have nervous systems — lack consciousness, the chances that plants without nervous systems have consciousness are effectively nil,” Taiz said. And what’s so great about consciousness, anyway? Plants can’t run away from danger, so investing energy in a body system that recognizes a threat and can feel pain would be a very poor evolutionary strategy, according to the article. “Being conscious may seem like harmless fun for plants being cared for in a garden, but imagine, for example, the plight of trees during a forest fire. I would not wish to inflict on trees the consciousness and pain of being burned alive,” Taiz said in the email. “Being unconscious is in all likelihood an advantage to plants and contributes to their evolutionary fitness,” he added. The findings were published online July 3 in the journal Trends in Plant Science. What Distinguishes Humans from Other Animals?last_img read more

Nearly 73 per cent polling recorded in Mizoram pollsNearly 73 per cent

first_imgMizoram SHARE Published on COMMENTS elections November 28, 2018 COMMENT SHARE SHARE EMAIL Around 73 per cent votes were cast in the Mizoram assembly polls on Wednesday but the figure is expected to rise as there were long queues of voters outside polling booths to exercise their franchise, Chief Electoral Officer Ashish Kundra said.Polling was held in all the 40 assembly seats.Kundra told reporters that the highest turnout of 81 per cent was reported at Serchhip seat, where Chief Minister Lal Thanhawla is one of the contestants.At Kanhmun village in Mamit district bordering Tripura where Bru refugees lodged in Tripura camps cast their votes, 52 per cent of the 118,987 electorate exercised their franchise, he said.“This is satisfactory considering the circumstances,” he said.The polling in Kanhmun ended at 3 pm, while for the rest of the state the time was 4 pm.“I congratulate the Mizo people for free, fair and peaceful elections. My special gratitude to the Mizo civil society, particularly Young Mizo Association. They helped the election authority in every possible manner… ,” said Kundra, who had replaced S B Shahshank less than a fortnight before the polls.Shahshank had been removed by the Election Commission following large-scale protests by civil societies after he complained against Mizoram’s Principal Secretary (home) Lalninmawia Chuaungo for playing an active role in the revision of electoral roll of Bru refugees lodged in the Tripura camps since 1997.last_img read more

AP building up right ecosystem for startups Winny Patro

first_imgWinny Patro, CEO, AP Innovation Society Andhra Pradesh The Andhra Pradesh government is laying emphasis on promoting emerging technologies and stimulating innovation to build up the right ecosystem for young entrepreneurs, especially for setting up start-ups, according to AP Innovation Society CEO Winny Patro.He said here that “earnest efforts are being made to draw not only young entrepreneurs from the State and the country, but even from abroad, to launch operations here, Amaravati, Tirupati, Anantapur and other places.”He said hackathons were being held regularly and the State gGovernment had tied up with agencies in Hong Kong and Israel to enable youngsters to pitch their innovative ideas and come forward to start their ventures with solutions to problems faced by the people and various corporates.He said that in the Slush-2018, a prestigious start-up event being organised in Helsinki (Finland) on December 4 and 5, out of 30 start-ups 10 based in AP had been selected for participation by the Department of Industrial Policy and Promotion.Patra said the State government was encouraging out-of-the-box ideas from youngsters to convert them later into commercial ventures. “We are adopting various strategies to strengthen the start-up ecosystem by providing a network of venture capital funding firms, mentorship, incubation and acceleration. Selected global companies in various hackathons are also asked to start their operations in the State after offering them several incentives,” he added. Published on COMMENTS SHAREcenter_img start ups SHARE SHARE EMAIL COMMENT November 28, 2018last_img read more

Railways to recruit 13 lakh people 13000 hires to be made under

first_imgH.P. to implement 10% quota for general category soon: CM 10 per cent quota Bill challenged in Apex court January 23, 2019 10 PER CENT QUOTAThe 124th Amendment: A look at the facts Passage of quota Bill victory of social justice: Modi COMMENT RELATED SHARE SHARE EMAIL The Railways plans to be the first government department to hire people under the 10 per cent quota for the Economical Weaker Section (EWS). About 13,000 people will join the organisation in the first phase of hiring under the newly announced quota. The first phase of fresh recruitment for 1,31,328 posts shall be initiated in February-March 2019, said an official release. Around 10 per cent of these vacancies (around 13,100) shall be filled in from the EWS. This recruitment shall be completed by April-May 2020. First ministry“Railways will be the first ministry to start the hiring process with a 10 per cent quota for the economic weaker section,” Railway Minister Piyush Goyal said here on Wednesday. The first phase, to hire 1.32 lakh employees, will start after a tender for selection of the examination agency, he added.With approximately 53,000 and 46,000 employees retiring in 2019-20 and 2020-21 respectively, an additional 99,000 posts will be vacant. This will result in demand for almost 2.3 lakh vacancies, creating opportunities for 23,000 posts for the EWS in two phases.The recruitment for 1.51 lakh posts is on, leaving over 1.31 posts vacant. 10% EWS quota due to political will of my govt: Modi SHARE Amid quota battle, govts yet to fill 28 lakh jobs Published on Aims to be first ministry to hire under EWS quota UP govt nod to quota for poor among upper castes Reservation COMMENTSlast_img read more

Unhappy with Yamuna cleaning NGT asks Delhi UP Haryana to deposit Rs

first_imgenvironmental pollution The National Green Tribunal on Tuesday expressed dissatisfaction over the cleaning of river Yamuna and directed Delhi, Haryana and Uttar Pradesh governments to submit a performance guarantee of Rs 10 crore each within a month. A bench headed by NGT chairperson Justice Adarsh Kumar Goel directed the state governments to furnish a performance guarantee with the Central Pollution Control Board (CPCB) to ensure there was no further lapse in this regard.The tribunal also warned that chief secretary of all the three states would be personally liable for any non-compliance.The green panel made it clear that the amount will be forfeited if the work was not carried out as per the recommendations of the monitoring committee constituted by it and asked the panel to expeditiously submit its final report.It directed that steps be taken by the three states at the earliest for disposal of municipal solid waste, cleaning of drains and ensuring cleaning of garbage.The order came after perusing the interim report filed by the monitoring committee comprising retired expert member B S Sajwan and former Delhi chief secretary Shailaja Chandra.The monitoring committee in its action plan submitted has recommended a study to assess the environmental flow of Yamuna river for the stretch between Hathanikund and Okhla. It said the river was “fighting to stay alive” and it would not be possible to rejuvenate it unless minimum environmental flow was provided.With regard to idol immersion, the committee has asked the authorities in the city to look for the possibility of creating artificial ponds and pits in various localities. The NGT had earlier asked the Haryana and Uttar Pradesh governments to consult the members of the monitoring committee appointed by the tribunal for constituting their own full time committees.The tribunal had expressed displeasure that despite its specific order, the status of the compliance was unknown, and said there appeared to failure of the authorities in performing their duties, thus undermining the rule of law.The green panel had said pollution in the Yamuna was of serious concern as it was highly contaminated with industrial effluents and sewage.It had also asked the Haryana pollution control board to conduct a study of water quality and the flow of Yamuna at the point it enters Haryana, and submit the list of industries located in the catchment area.The green panel had noted that almost 67 per cent of the pollutants that enter the Yamuna would be treated by two sewage treatment plants at Delhi Gate and Najafgarh under the first phase of the Maili se Nirmal Yamuna Revitalisation project. SHARE SHARE EMAIL The tribunal also warned that chief secretary of all the three states would be personally liable for any non-compliance COMMENTS A view of National Green Tribunal (NGT), in New Delhi – THE HINDU January 29, 2019 SHARE environmental cleanup Published on COMMENTlast_img read more

Bombay HC upholds reservation for Maratha community but says 16 not justifiable

first_imgA view of the Bombay High Court – BusinessLine SHARE SHARE EMAIL Directs quota to be reduced from the present 16 to 12-13 per cent Maharashtra Reservation COMMENT The Bombay High Court on Thursday upheld the constitutional validity of reservation for the Maratha community in government jobs and education but said the quota should be reduced from the present 16 per cent to 12 to 13 per cent.A division bench of Justices Ranjit More and Bharati Dangre said the quota percentage should be reduced as recommended by the State Backward Classes Commission.The commission in it report earlier recommended 12 per cent quota in education and 13 per cent in jobs.“We hold and declare that the state government possesses legislative competence to create a separate category of Socially and Educationally Backward Class (SEBC) and grant reservation,” the court said. “We, however, have held that the 16 per cent (quota) should be reduced to 12 to 13 per cent, as recommended by the commission,” the bench said.The court further held that the state’s legislative competence is not affected by the amendment to Article 342(a) of the Constitution of India.As per the 102nd amendment to Article 342(a), reservation can be granted only if a particular community is named in the list prepared by the President of India.“We conclude that the report submitted by the State Backward Classes Commission was based on quantifiable data and was correct in classifying the Maratha community as socially and educationally backward,” the bench said in its judgment.The court said it was aware the Supreme Court in the past said the quota should not exceed 50 per cent.“However, in exceptional circumstances, the 50 per cent (limit) can be exceeded if it is based on quantifiable data,” the court said.Admissions in post graduate medical courses Soon after the judgment was delivered, the state government told the court that it has already granted admissions in post graduate medical courses under the reservation up to 16 per cent.Government counsel V A Thorat sought permission to let the percentage remain 16 per cent for these courses this year.The bench asked the government to file a separate application for this.The court was hearing a bunch of petitions challenging the state government’s decision granting 16 per cent reservation to the Maratha community in government jobs and educational institutions.On November 30, 2018, the Maharashtra legislature passed a bill granting 16 per cent reservation in education and government jobs for the Marathas, declared a socially and educationally backward class by the government.The reservation will be in addition to the existing 52 per cent reservation in the state.Several petitions were filed in HC challenging the reservation, while few others were filed in its support. Published on SHARE 0 courts and legal June 27, 2019 COMMENTSlast_img read more